Products

10-FnIII anti-FGFR2 (SFN-L033)

The tenth fibronectin type III domain (10Fn3) that bound fibroblast growth factor (FGF) receptor was isolated from the library using Phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=3 μM) for fibroblast growth factor (FGF) receptor as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
10-FnIII
Origin
neuronal cell adhesion
molecule L1
Core Structure
β-sandwich of 7 β-strands
Variable Regions
2–3 Loops
Target
Fibroblast growth factor (FGF) receptor
Species Reactivity
Human
Expression Host
E. coli
Affinity Constant
3 μM
Applications
ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
Alternative Names
neuronal cell adhesion molecule L1; 10-FnIII; BEK; JWS; BBDS; CEK3; CFD1; ECT1
Entrez Gene ID
2263
UniProt ID
P21802

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2017 Creative-Biolabs All Rights Reserved