The tenth fibronectin type III domain (10Fn3) that bound IL-23 was isolated from the library using Phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=0.26 nM) for IL-23 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-419CL | Human Anti-IL23 Recombinant Antibody (TAB-419CL) | Inhib, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-402CL | Afuco™ Anti-IL23 Recombinant Antibody (AFC-402CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1332CQ | Mouse Anti-IL23 Recombinant Antibody (clone B-Z23) | Neut, ICC, IF | Mouse IgG1 |
NEUT-1333CQ | Mouse Anti-IL23 Recombinant Antibody (clone MT155) | Neut | Mouse IgG2b |
NEUT-1334CQ | Rat Anti-Il23 Recombinant Antibody (clone G23-8) | Neut, WB, FuncS, ELISA | Rat IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0262-FY | Human Anti-IL23 Recombinant Antibody (HPAB-0262-FY) | ELISA | Human IgG1 |
HPAB-AP686-YC | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6) | ELISA | Mouse IgG |
HPAB-AP687-YC | Human Anti-IL23 Recombinant Antibody (clone ch8C92H6) | ELISA | Chimeric (mouse/human) IgG |
HPAB-AP688-YC | Human Anti-IL23 Recombinant Antibody (clone A24AM18) | ELISA, Neut | Humanized (mouse/human) IgG |
HPAB-AP689-YC | Human Anti-IL23 Recombinant Antibody (clone A5M20) | ELISA, Neut | Humanized (mouse/human) IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0360-WJ-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone m1A11); Fab Fragment | ELISA | Mouse Fab |
HPAB-0361-WJ-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone m11C1); Fab Fragment | ELISA | Mouse Fab |
HPAB-0362-WJ-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone m5F5); Fab Fragment | ELISA | Mouse Fab |
HPAB-0363-WJ-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone m21D1); Fab Fragment | ELISA | Mouse Fab |
HPAB-0364-WJ-F(E) | Mouse Anti-IL23 Recombinant Antibody (clone m13B8); Fab Fragment | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP686-YC-S(P) | Mouse Anti-IL23 Recombinant Antibody (clone 8C92H6); scFv Fragment | ELISA | Mouse scFv |
HPAB-AP687-YC-S(P) | Human Anti-IL23 Recombinant Antibody (clone ch8C92H6); scFv Fragment | ELISA | Mouse scFv |
HPAB-AP688-YC-S(P) | Human Anti-IL23 Recombinant Antibody (clone A24AM18); scFv Fragment | ELISA, Neut | Human scFv |
HPAB-AP689-YC-S(P) | Human Anti-IL23 Recombinant Antibody (clone A5M20); scFv Fragment | ELISA, Neut | Human scFv |
HPAB-AP690-YC-S(P) | Human Anti-IL23 Recombinant Antibody (clone A5M21); scFv Fragment | ELISA, Neut | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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