The tenth fibronectin type III domain (10Fn3) that bound phospho-IkappaBalpha peptide was isolated from the library using mRNA Display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=18 nM) for phospho-IkappaBalpha peptide as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1106MZ | Recombinant Mouse Anti-Human NFKBIA Antibody (clone 6A055) | WB | Mouse antibody |
VS3-QX812 | Mouse Anti-NFKBIA Recombinant Antibody (clone 1A10) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
VS3-QX813 | Mouse Anti-NFKBIA Recombinant Antibody (clone 1121CT8.6.1) | WB | Mouse IgG1, κ |
VS3-CJ826 | Mouse Anti-NFKBIA Recombinant Antibody (VS3-CJ826) | WB | Mouse IgG1, κ |
VS3-CJ827 | Rabbit Anti-NFKBIA (phospho S32) Recombinant Antibody (VS3-CJ827) | WB, ICC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2435 | Hi-Affi™ Recombinant Rabbit Anti-NFKBIA Monoclonal Antibody (DS2435AB) | ICC, IP, WB | IgG |
MOR-4603 | Hi-Affi™ Recombinant Rabbit Anti-NFKBIA Monoclonal Antibody (TH116DS) | WB, IHC-P | IgG |
MOR-4604 | Hi-Affi™ Recombinant Rabbit Anti-NFKBIA Monoclonal Antibody (TH117DS) | WB | IgG |
MOR-4686 | Hi-Affi™ Recombinant Rabbit Anti-NFKBIA Monoclonal Antibody (TH200DS) | WB, FC | IgG |
MOR-0076-FY | Rabbit Anti-NFKBIA Recombinant Antibody (clone AFY0047) | IF, IHC-P, WB | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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