The tenth fibronectin type III domain (10Fn3) that bound TNF-a was isolated from the library using mRNA Display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=20 pM) for TNF-a as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
NABL-051 | Recombinant Anti-human TNF VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
TAB-412CQ | Anti-Human TNF Therapeutic Single Domain Antibody (TAR1-5-19) | ELISA, Inhib | Single domain antibody |
TAB-413CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL18) | ELISA, WB, Neut | Single domain antibody |
TAB-414CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL11) | ELISA, WB, Neut | Single domain antibody |
TAB-415CQ | Anti-Human TNF Therapeutic Single Domain Antibody (VL18-3L-VL11) | ELISA, WB, Neut, FunS | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-768 | Anti-TNF alpha Recombinant Antibody (Nerelimomab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 |
TAB-123CQ-F(E) | Mouse Anti-TNF Recombinant Antibody; Fab Fragment (TAB-123CQ-F(E)) | ELISA, Neut | Mouse Fab |
TAB-130CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (m357) | ELISA, FC, Neut | |
TAB-132CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (MAK195) | ELISA, Neut | |
TAB-139CQ-F(E) | Rabbit Anti-TNF Recombinant Antibody; Fab Fragment (TAB-139CQ-F(E)) | ELISA, FC, IF | Rabbit Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-623CL | Bovine Anti-TNF Recombinant Antibody (TAB-623CL) | Neut | Bovine IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-124CQ | Human Anti-TNF Recombinant Antibody (TAB-124CQ) | FuncS, Neut | Humanized antibody |
TAB-125CQ | Human Anti-TNF Recombinant Antibody (TAB-125CQ) | ELISA, Neut | Humanized antibody |
TAB-126CQ | Human Anti-TNF Recombinant Antibody (TAB-126CQ) | ELISA, Neut | Humanized antibody |
TAB-127CQ | Human Anti-TNF Recombinant Antibody (TAB-127CQ) | ELISA, Neut | Humanized antibody |
TAB-128CQ | Human Anti-TNF Recombinant Antibody (TAB-128CQ) | ELISA, FuncS | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-148CQ | Anti-Human TNF Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
TAB-402CQ | Human Anti-TNF Recombinant Antibody (TAB-402CQ) | ELISA | Chimeric (mouse/human) IgG |
TAB-148CQ-S(P) | Anti-Human TNF Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
TAB-402CQ-S(P) | Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) | ELISA | Mouse scFv |
TAB-148CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-135CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (AE11-5) | ELISA, Neut | Human antibody |
TAB-136CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-136CQ-F(E)) | ELISA, Block | Human Fab |
TAB-137CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-137CQ-F(E)) | ELISA, FC, IF | Human Fab |
TAB-138CQ-F(E) | Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-138CQ-F(E)) | ELISA, FC, IF | Human Fab |
TAB-140CQ-F(E) | Anti-Human TNF Recombinant Antibody Fab Fragment (G1) | FC, Neut | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-083LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
Gly-085LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA, FC | Human antibody |
Gly-086LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Gly-087LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Gly-163LC | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-083LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) | ELISA, FC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-085LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA, FC | Human antibody |
Gly-163LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-086LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
Gly-087LC-1 | Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA, FC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0229MZ | Recombinant Mouse Anti-Human TNF Antibody (clone G7C6) | ELISA, IHC | Mouse antibody |
HPAB-0675-CN | Human Anti-TNF Recombinant Antibody (HPAB-0675-CN) | ELISA, Neut | Humanized IgG |
HPAB-0676-CN | Human Anti-TNF Recombinant Antibody (HPAB-0676-CN) | ELISA, Neut | Humanized IgG |
HPAB-0677-CN | Human Anti-TNF Recombinant Antibody (HPAB-0677-CN) | ELISA, Neut | Humanized IgG |
HPAB-0678-CN | Human Anti-TNF Recombinant Antibody (HPAB-0678-CN) | ELISA, Neut | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0609MZ | Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2057CQ | Rat Anti-Tnf Recombinant Antibody (clone XT3) | Block, ELISA, IHC, WB | Rat IgG1 |
NEUT-2070CQ | Mouse Anti-TNF Recombinant Antibody (clone 4F4) | Block, ELISA, ICC, IF, IHC, WB | Mouse IgG1 |
NEUT-2071CQ | Rabbit Anti-TNF Recombinant Antibody (clone 6E10) | Block, ELISA, IHC, WB | Rabbit IgG1 |
NEUT-2082CQ | Mouse Anti-TNF Recombinant Antibody (clone B-C7) | Block | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2098CQ | Mouse Anti-TNF Recombinant Antibody (clone 2.1_4E10-1H11) | ELISA, Neut, WB | Mouse IgG |
NEUT-2099CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL403) | Neut | Mouse IgG1 |
NEUT-2100CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL741) | WB, ELISA, ICC, Neut | Mouse IgG1 |
NEUT-2101CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL742) | ELISA, Neut | Mouse IgG1 |
NEUT-2102CQ | Mouse Anti-TNF Recombinant Antibody (clone CBL814) | ICC, Neut | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3602 | Rabbit Anti-Tnf Recombinant Antibody (clone DS3602AB) | ELISA, WB | Rabbit IgG |
MOR-4460 | Rabbit Anti-TNF Recombinant Antibody (clone SI554DS) | ELISA | Rabbit IgG |
MOR-4461 | Rabbit Anti-TNF Recombinant Antibody (clone SI555DS) | Neut | Rabbit IgG |
MOR-4462 | Rabbit Anti-TNF Recombinant Antibody (clone SI556DS) | FC | Rabbit IgG |
MOR-4463 | Rabbit Anti-TNF Recombinant Antibody (clone SI557DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0007-YC-F(E) | Human Anti-TNF Recombinant Antibody (clone cA2); Fab Fragment | ELISA, Neut | Human Fab |
HPAB-0321CQ-F(E) | Human Anti-TNF Recombinant Antibody (clone mAb A1); Fab Fragment | ELISA, Neut | Human Fab |
HPAB-0322CQ-F(E) | Rat Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0322CQ-F(E)) | ELISA, FC, Inhib | Rat Fab |
HPAB-0323CQ-F(E) | Rat Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0323CQ-F(E)) | ELISA, FC, Inhib | Rat Fab |
HPAB-1283LY-F(E) | Human Anti-TNF Recombinant Antibody (clone CBL026); Fab Fragment | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-768 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-006 | Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-010 | Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0513-WJ-S(P) | Human Anti-TNF Recombinant Antibody; scFv Fragment (HPAB-0513-WJ-S(P)) | ELISA | Human scFv |
HPAB-AP470-YC-S(P) | Mouse Anti-TNF Recombinant Antibody (clone E2); scFv Fragment | ELISA, Neut | Mouse scFv |
HPAB-2086-FY-S(P) | Mouse Anti-TNF Recombinant Antibody (clone 101.4); scFv Fragment | IA | Mouse scFv |
HPAB-2087-FY-S(P) | Mouse Anti-TNF Recombinant Antibody (clone CB0010); scFv Fragment | Neut | Mouse scFv |
HPAB-1564WJ-S(P) | Mouse Anti-TNF Recombinant Antibody; scFv Fragment (clone 3B10) | ELISA, WB, Neut | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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