The tenth fibronectin type III domain (10Fn3) that bound ubiquitin was isolated from the library using phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=27 nM) for ubiquitin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1022 | Recombinant Anti-Ubiquitin Antibody | ELISA, WB, Neut, FuncS | IgG |
MHH-1022 | Recombinant Human Anti-Ubiquitin Antibody | RIA, IP, FuncS | IgG |
ZG-0165C | Mouse Anti-Ubiquitin Recombinant Antibody (clone 5F1) | WB, IF/ICC, IHC-P | Mouse IgG |
ZG-0166C | Mouse Anti-Ubiquitin Recombinant Antibody (clone 6G6) | WB, IHC-P, IF | Mouse IgG |
ZG-460C | Mouse Anti-Ubiquitin Recombinant Antibody (clone C1) | ELISA, WB | Mouse IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1022-F(E) | Recombinant Anti-Ubiquitin Antibody Fab Fragment | IF, FuncS | Fab |
MHH-1022-F(E) | Recombinant Human Anti-Ubiquitin Antibody Fab Fragment | ELISA, WB, Dot, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1022-S(P) | Recombinant Anti-Ubiquitin Antibody scFv Fragment | FC, Neut, Funcs | scFv |
MHH-1022-S(P) | Recombinant Human Anti-Ubiquitin Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN1297 | PE-A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC | |
MHC-CN1298 | APC-A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC | |
MHC-CN1299 | FITC-A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC | |
MHC-CN1300 | A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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