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2-Helix small protein anti-ERBB2 (SHS-L035)

The 2-Helix small protein that bound HER2 was isolated from the library using Phage display techonology. After affinity maturation, 2-Helix small protein variants were identified having affinities for HER2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
2-Helix small protein
Origin
2-Helix small protein
Core Structure
2-α helixes
Variable Regions
13 Residues on 2-a helixes surface
Target
HER2
Species Reactivity
Human
Expression Host
BL21 (DE3) cells
Applications
ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
Alternative Names
2-Helix small protein; 2-Helix small protein; NEU; NGL; HER2; TKR1; CD340; HER-2
Entrez Gene ID
2064
UniProt ID
P04626

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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