PE-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer (CAT#: MHC-LC145)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of EphA2-derived peptide of TLADFDPRV sequence covering 883-891 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (CAPAN-2, PC-3, U-251 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- EphA2
- Antigen Species
- Human
- Peptide
- TLADFDPRV
- Range
- 883-891
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
- Alternative Names
- EPHA2; EPH receptor A2; ECK; CTPA; ARCC2; CTPP1; CTRCT6
- Gene ID
- 1969
- UniProt ID
- P29317
Downloads
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See other products for "EPHA2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1460z | Mouse Anti-EPHA2 Recombinant Antibody (clone 31G12) | WB, ELISA, ICC, IF | Mouse IgG2b, κ |
| PABL-083 | Human Anti-EPHA2 Recombinant Antibody (clone 1C1) | ELISA, WB, FuncS | Human IgG |
| MOB-0650CT | Recombinant Mouse anti-Human EPHA2 Monoclonal antibody (EML298) | WB | |
| HPAB-0336-YC | Mouse Anti-EPHA2 Recombinant Antibody (HPAB-0336-YC) | ELISA, FC, FuncS | Mouse IgG2a |
| ZG-0293J | Mouse Anti-EPHA2 Recombinant Antibody (ZG-0293J) | WB, IHC, ELISA | Mouse IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-381MZ | Anti-Human EPHA2 Recombinant Antibody (LUCA40) | FC | |
| TAB-382MZ | Anti-Human EPHA2 Recombinant Antibody (SPL1) | IHC, WB, sELISA | |
| TAB-383MZ | Anti-Human EPHA2 Recombinant Antibody (SG5 ) | IHC, WB, sELISA | |
| TAB-384MZ | Mouse Anti-EPHA2 Recombinant Antibody (TAB-384MZ) | ELISA | Mouse IgG |
| TAB-380MZ-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-380MZ-S(P)) | IHC, WB, sELISA | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-385MZ | Human Anti-EPHA2 Recombinant Antibody (TAB-385MZ) | ELISA | Humanized IgG |
| TAB-385MZ-S(P) | Human Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-385MZ-S(P)) | ELISA | Humanized scFv |
| TAB-385MZ-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (TAB-385MZ-F(E)) | ELISA | Humanized Fab |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC146 | APC-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer | FCM | |
| MHC-YF418 | A*02:01/Human EPHA2 (VLAGVGFFI) MHC Pentamer | FCM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1164 | Hi-Affi™ Rabbit Anti-EPHA2 Recombinant Antibody (clone DS1164AB) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0336-YC-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (HPAB-0336-YC-S(P)) | ELISA, FC, FuncS | Mouse scFv |
| HPAB-0337-YC-S(P) | Human Anti-EPHA2 Recombinant Antibody; scFv Fragment (HPAB-0337-YC-S(P)) | ELISA, FC, FuncS | Humanized scFv |
| HPAB-0338-YC-S(P) | Human Anti-EPHA2 Recombinant Antibody (clone 2E7); scFv Fragment | ELISA | Human scFv |
| HPAB-0339-YC-S(P) | Mouse Anti-EPHA2 Recombinant Antibody (clone EA5); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
| HPAB-0777-FY-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0777-FY-F(E)) | ELISA | Human Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0450-CN-F(E) | Mouse Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0450-CN-F(E)) | ELISA, WB, FC, IP | Mouse Fab |
| HPAB-0452-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0452-CN-F(E)) | ELISA, WB, FC, IP | Humanized Fab |
| HPAB-0453-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone 4H5); Fab Fragment | ELISA, FC, IF | Humanized Fab |
| HPAB-0454-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone 2A4); Fab Fragment | ELISA, FC, IF, Agonist | Humanized Fab |
| HPAB-0455-CN-F(E) | Mouse Anti-EPHA2 Recombinant Antibody (clone EA2); Fab Fragment | ELISA, FC, IF | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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