Products

Adalimumab (TP-086CL)

Adalimumab is a human monoclonal antibody against TNF-alpha. It is produced by recombinant DNA technology using a mammalian cell expression system. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.      

Specifications
Classify
Protein therapeutics that interfere with a molecule or organism: Immunoregulation
Therapeutic
Adalimumab
Trade Name
Humira
Function
Human mAb that binds specifically to TNFa and blocks its interaction with p55 and p75 cell surface TNF receptors, resulting in decreased levels of inflammation markers including crP, esr, and iL6
Examples of Clinical Use
Rheumatoid arthritis, crohn's disease, ankylosing spondylitis, psoriatic arthritis
References
Synonyms
Ig gamma-1 chain C region
UniProt
P01857
Genbank
J00228

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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