Products

Alemtuzumab (TP-081CL)

Humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein,CD52. The Campath-1H antibody is an IgG1 kappa with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G). Campath is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.      

Specifications
Classify
Protein therapeutics that interfere with a molecule or organism: Cancer
Therapeutic
Alemtuzumab
Trade Name
Campath
Function
Humanized mAb directed against cD52 antigen on T and B cells
Examples of Clinical Use
B-cell chronic lymphocytic leukaemia in patients who have been treated with alkylating agents and who have failed fludabarine therapy
References
Synonyms
Not Available

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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