Products

Anakinra (TP-085CL)

Anakinra is a recombinant, nonglycosylated human interleukin-1 receptor antagonist (IL-1Ra). The difference between anakinra and the native human IL-1Ra is that anakinra has an extra methionine residue at the amino terminus. It is manufactured by using the E. coli expression system. Anakinra is composed of 153 amino acid residues. FDA approved on November 14, 2001.      

Specifications
Classify
Protein therapeutics that interfere with a molecule or organism: Immunoregulation
Therapeutic
Anakinra
Trade Name
Antril, Kineret
Function
Recombinant interleukin 1 (iL1) receptor antagonist
Examples of Clinical Use
Moderate to severe active rheumatoid arthritis in adults who have failed one or more disease- modifying antirheumatic drug
References
Synonyms
ICIL-1RA, IL-1ra, IL-1RN, IL1 inhibitor, Interleukin-1 receptor antagonist protein precursor, IRAP
UniProt
P18510
Genbank
M55646

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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