Ankyrin repeat scaffold protein anti-Human IL13 (CAT#: SAR-L262)

The Ankyrin repeat that bound IL13 was isolated from the library using ribosome display techonology. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops, first discovered in signaling proteins in yeast Cdc10 and Drosophila Notch. Domains consisting of ankyrin repeats mediate protein–protein interactions and are among the most common structural motifs in known proteins. After affinity maturation, Ankyrin repeat variants were identified having affinities (KD=1.7 pM) for IL13 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.


Specific Inquiry
  • Size:
  • Conjugation:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Scaffold Name
  • Ankyrin repeat
  • Origin
  • Ankyrin repeat proteins
  • Core Structure
  • 2α-helices, β-turn
  • Variable Regions
  • b-turn,1a-helix and loop
  • Target
  • IL13
  • Species Reactivity
  • Human
  • Expression Host
  • BL21 (DE3) cells
  • Affinity Constant
  • 1.7 pM
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • P600; IL-13

Related Resources

  • Related Diseases

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "IL13"

Human Antibody

CAT Product Name Application Type
TAB-218 Anti-Human IL13 Recombinant Antibody (Tralokinumab) ELISA, FC, IP, FuncS, IF, Neut, ICC IgG4 - lambda
TAB-068ZJ Anti-Human IL-13 Recombinant Antibody (01471/G6) WB, ELISA, Neut Human antibody
TAB-069ZJ Human Anti-IL13 Recombinant Antibody (TAB-069ZJ) ELISA, Neut, FC Human IgG
TAB-070ZJ Human Anti-IL13 Recombinant Antibody (TAB-070ZJ) ELISA, Neut, FC Human IgG
TAB-017ML Anti-Human IL13 Recombinant Antibody (Dectrekumab) ELISA, IHC, FC, IP, IF, Inhib IgG1, κ

Recombinant Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-094ZJ Anti-Human IL-13 Recombinant Antibody (167) ELISA Chimeric antibody (mouse/human)
TAB-094ZJ-S(P) Anti-Human IL-13 Recombinant Antibody scFv Fragment (167) ELISA Chimeric antibody (mouse/human)
TAB-094ZJ-F(E) Anti-Human IL-13 Recombinant Antibody Fab Fragment (167) ELISA Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H05 Afuco™ Anti-IL13 ADCC Recombinant Antibody (Anrukinzumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-017ML Afuco™ Anti-IL13 ADCC Recombinant Antibody (Dectrekumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody
AFC-TAB-219 Afuco™ Anti-IL13 ADCC Recombinant Antibody (Lebrikizumab), ADCC Enhanced ELISA, Neut, IF, IP, FC, FuncS ADCC enhanced antibody
AFC-TAB-218 Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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