Recombinant Anti-human Aβ42 Intrabody [+36 GFP] (CAT#: IAB-B042(G))

Recombinant anti-Aβ42 intrabody in fusion with +36GFP works within cells to bind intracellur Aβ42, expressed in E. coli cells. The intrabodies, one with an endoplasmic reticulum (ER) targeting signal and one devoid of a targeting sequence, were assessed in cells harboring a doxycycline (Dox)-regulated mutant human amyloid precursor protein Swedish mutant (hAPPswe) transcription unit for their abilities to prevent Aβ peptide egress.


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Specifications

  • Immunogen
  • human Amyloid β Peptide 42
  • Host Species
  • human
  • Type
  • scFv-(+36GFP)
  • Cell Penetrating Peptide
  • +36 GFP
    GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
  • Species Reactivity
  • human
  • Applications
  • Products can be used for: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Neutralization; Functional studies

Product Property

  • Purity
  • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
  • Storage
  • ≤1 year at -20°C.

Target

  • Alternative Names
  • Aβ42; Amyloid β Peptide 42

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Aβ42"

Recombinant Antibody

Intrabody

CAT Product Name Application Type
IAB-B042(A) Recombinant Anti-human Aβ42 Intrabody [(D-Arg)9] CO-IP, FuncS scFv-(D-Arg)9
IAB-B042(T) Recombinant Anti-human Aβ42 Intrabody [Tat] ELISA, Neut, FuncS scFv-Tat

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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