Anti-Human ADAM12 Recombinant Antibody (7B8) (CAT#: TAB-0665CLV)

The anti-ADAM12 antibody target A Disintegrin And Metal loprotease12 which is highly upregulated in a variety of human cancers including breast, bladder, laryngeal and lung carcinomas.


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IF

Figure 1 Monoclonal antibodies against ADAM12 inhibit ADAM12-induced gelatin degradation.

Figure 1 Monoclonal antibodies against ADAM12 inhibit ADAM12-induced gelatin degradation.

In situ solid-phase gelatinase assay of 293-VnR cells transfected with ADAM12Dcyt and treated overnight with 4 mg/ml of mAbs against ADAM12 (6E6, 7B8 and 8F8). Dishes were stained using the ADAM12 monoclonal antibody 6E6 (red) and DAPI (blue).

Albrechtsen, R., Kveiborg, M., Stautz, D., Vikeså, J., Noer, J. B., Kotzsh, A., ... & Fröhlich, C. (2013). ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth. J Cell Sci, 126(20), 4707-4720.


Specifications

  • Immunogen
  • full-length ADAM 12-S
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Clone
  • 7B8
  • Applications
  • IF
  • Related Disease
  • Breast cancer, bladder cancer, laryngeal cancer, lung carcinomas

Applications

  • Application Notes
  • The ADAM12 antibody has been reported in applications of Immunofluorescence.

Target

  • Alternative Names
  • ADAM12; ADAM metallopeptidase domain 12; MCMP; MLTN; CAR10; MLTNA; MCMPMltna; ADAM12-OT1; disintegrin and metalloproteinase domain-containing protein 12; meltrin-alpha; metalloprotease-disintegrin 12 transmembrane

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 7B8"

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Recombinant Antibody

CAT Product Name Application Type
MOB-0435MZ Mouse Anti-ADAM12 Recombinant Antibody (clone 632525) WB Mouse IgG1

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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