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Anti-ADAMTS4 scFv (7E8.1E3) (TAB-0677CLV-S(P))

The anti-ADAMTS4 antibody target ADAMTS4 that is kind of aggrecanases of which the activities can result in the degradation of the cartilage matrix. By inhibiting ADAMTS4 and thereby reducing the breakdown of extracellular matrix aggrecan in cartilage and other tissues, the antibody can be used in the treatment of diseases of cartilage.      

Specifications
Immunogen
ADAMTS4, ADAMTS5
Host
Mouse
Specificity
Human
Species Reactivity
Cross-react with rat ADAMTS4
Clone
7E8.1E3
Related Disease
Diseases of cartilage
Target
Alternative Names
ADAM metallopeptidase with thrombospondin type 1 motif, 4; ADAM-TS 4; ADMP-1; EC 3.4.24.82; KIAA0688; A disintegrin and metalloproteinase with thrombospondin motifs 4; aggrecanase-1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospo
Entrez Gene ID
9507
UniProt ID
O75173

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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