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Anti-ADAMTS5 Therapeutic Antibody (2D3.1D4) (TAB-0687CLV)

The anti-ADAMTS5 antibody target ADAMTS5 that is kind of aggrecanases of which the activities can result in the degradation of the cartilage matrix. By inhibiting ADAMTS5 and thereby reducing the breakdown of extracellular matrix aggrecan in cartilage and other tissues, the antibody can be used in the treatment of disease of cartilage.      

Specifications
Immunogen
ADAMTS4, ADAMTS5
Host
Mouse
Specificity
Human
Species Reactivity
Cross-react with cynomolgus and canine ADAMTS5
Clone
2D3.1D4
Related Disease
Diseases of cartilage
Target
Alternative Names
ADAMTS5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11
Entrez Gene ID
11096
UniProt ID
Q9UNA0

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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