Mouse Anti-APP Recombinant Antibody (clone WO2) (CAT#: PABL-404)

Recombinant Mouse Antibody (WO2) is capable of binding to APP. This recognizes Aβ residues 3–7 the N-terminus of the APP.


Specific Inquiry
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  • Purity:
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Figure 1 Western blot analysis of monoclonal antibody WO2 in transgenic Tg2576 and background control strain (C57B6 X SJL) mice at 4, 8 and 12 months of age.

Figure 1 Western blot analysis of monoclonal antibody WO2 in transgenic Tg2576 and background control strain (C57B6 X SJL) mice at 4, 8 and 12 months of age.

Brains were homogenized as described and extracts applied to 15% Tris‐tricine SDS–PAGE. The migration of the molecular weight markers are shown. Data represents the increase in total Aβ levels in Tg2576 mice as they age.

Fodero, L. R., Sáez‐Valero, J., McLean, C. A., Martins, R. N., Beyreuther, K., Masters, C. L., ... & Small, D. H. (2002). Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition. Journal of neurochemistry, 81(3), 441-448.


Specifications

  • Immunogen
  • Human amyloid beta (A4) precursor protein
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • APP
  • Species Reactivity
  • Human
  • Clone
  • WO2
  • Applications
  • WB, ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • APP; amyloid beta (A4) precursor protein; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); alzheimer disease amyloid protein; cerebral vascular amyloid peptide

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Recombinant Antibody

Single-domain Antibody

CAT Product Name Application Type
TAB-0019CL-VHH Camelid Anti-APP Recombinant Antibody (TAB-0019CL-VHH) IHC, WB Camelid VHH
TAB-0020CL-VHH Anti-Human APP VHH Single Domain Antibody (MPL D7) ELISA, IHC Single domain antibody
TAB-0021CL-VHH Anti-Human APP VHH Single Domain Antibody (MPL C2) ELISA, In vivo, FuncS Single domain antibody
TAB-0022CL-VHH Anti-Human APP VHH Single Domain Antibody (MPL H3) ELISA, In vivo, FuncS Single domain antibody
TAB-0023CL-VHH Anti-Human APP VHH Single Domain Antibody (MPL H6) ELISA, In vivo, FuncS Single domain antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0685MZ Chicken Anti-APP Polyclonal IgY IHC Chicken antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-225 Afuco™ Anti-APP ADCC Recombinant Antibody (Bapineuzumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-228 Afuco™ Anti-APP ADCC Recombinant Antibody (Solanezumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-229 Afuco™ Anti-APP ADCC Recombinant Antibody (Gantenerumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-227 Afuco™ Anti-APP ADCC Recombinant Antibody (Ponezumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
AFC-TAB-226 Afuco™ Anti-APP ADCC Recombinant Antibody (Crenezumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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