Afuco™ Anti-Human AXL ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-056CL)
Anti-AXL ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Anti-AXL antibodies can bind to a specific region in Anexelekto (AXL) and are useful as agents for decreasing the AXL expression level, antitumor agents, and diagnostic agents for cancer.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
Figure 2 IHC staining of human thyroid gland
(Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
(Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
Figure 3 Skeletal muscle
(Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
(Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7
- Gene ID
- 558
- UniProt ID
- P30530
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "AXL"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2240z | Mouse Anti-AXL Recombinant Antibody (clone 23F11) | WB, ELISA, IF, IHC | Mouse IgG1 |
| MOB-0872MZ | Mouse Anti-AXL Recombinant Antibody (clone 1B3A2) | WB | Mouse IgG1 |
| HPAB-0600-CN | Human Anti-AXL Recombinant Antibody (HPAB-0600-CN) | SPR, ELISA, FC, WB, Inhib, FuncS, IHC, Block | Human IgG |
| HPAB-0601-CN | Human Anti-AXL Recombinant Antibody (HPAB-0601-CN) | ELISA, FC, IHC, Block | Human IgG |
| HPAB-0603-CN | Human Anti-AXL Recombinant Antibody (HPAB-0603-CN) | WB, ELISA, FC, IHC | Chimeric (Mouse/Human) IgG1, κ |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0139CL | Anti-Human AXL Recombinant Antibody (hzl613F12-24 DAR2) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
| TAB-0140CL | Anti-Human AXL Recombinant Antibody (hzl613F12-33 DAR4) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
| TAB-1094CL | Anti-Human AXL Recombinant Antibody (Hz1613F12) | ELISA, FC, Cyt | Humanized antibody |
| TAB-0139CL-F(E) | Anti-Human AXL Recombinant Antibody Fab Fragment (hzl613F12-24 DAR2) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
| TAB-0140CL-F(E) | Anti-Human AXL Recombinant Antibody Fab Fragment (hzl613F12-33 DAR4) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0189CL | Human Anti-AXL Recombinant Antibody (TAB-0189CL) | WB, FuncS, ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
| TAB-1090CL | Human Anti-AXL Recombinant Antibody (TAB-1090CL) | ELISA, FuncS | Chimeric (mouse/human) IgG1, κ |
| TAB-1091CL | Human Anti-AXL Recombinant Antibody (TAB-1091CL) | ADCC | Chimeric (mouse/human) IgG1, κ |
| TAB-1092CL | Human Anti-AXL Recombinant Antibody (TAB-1092CL) | ADCC | Chimeric (mouse/human) IgG1, κ |
| TAB-1090CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1090CL-F(E)) | ELISA, FuncS | Chimeric (mouse/human) Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0335CL | Anti-Human AXL Recombinant Antibody (Ax225 (was demonstrated to recognize FND1 of AXL)) | WB, FuncS, ELISA | |
| TAB-0336CL | Anti-Human AXL Recombinant Antibody | WB, FuncS, ELISA | |
| TAB-1087CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1087CL-S(P)) | ELISA, FuncS | Mouse scFv |
| TAB-1088CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1088CL-S(P)) | ELISA, FuncS | Mouse scFv |
| TAB-1089CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1089CL-S(P)) | ELISA, FuncS | Mouse scFv |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3970 | Hi-Affi™ Rabbit Anti-AXL Recombinant Antibody (clone SI30DS) | ELISA | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0108-LS-F(E) | Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-0108-LS-F(E)) | ELISA | Mouse Fab |
| HPAB-0109-LS-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-0109-LS-F(E)) | ELISA, FC, IHC, Block | Human Fab |
| HPAB-0110-LS-F(E) | Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-0110-LS-F(E)) | WB, Agonist | Mouse Fab |
| HPAB-0112-LS-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-0112-LS-F(E)) | Block | Human Fab |
| HPAB-0113-LS-F(E) | Mouse Anti-AXL Recombinant Antibody (clone AXL225); Fab Fragment | Inhib | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1864LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1864LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1865LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1865LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1866LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1866LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1867LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1867LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1868LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1868LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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