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Anti-C1S Fab (IPN003) (TAB-0087CL-F(E))

Anti-C1s antibody is a humanized monoclonal antibody that targets the complement C1s protein, which is an attractive target for its upstream location in the complement cascade and narrow range of substrate specificity. The binding of C1s with antibody would inhibit cleavage of C4 by C1s.      

Specifications
Immunogen
Human activated C1s protein
Host
Mouse
Specificity
Human
Species Reactivity
Cross-reacts with C1s from at least two monkey species
Clone
IPN003
Related Disease
Complement-mediated disease or disorder, age-related macular degeneration, Alzheimer's disease, amyotrophic lateral sclerosis, anaphylaxis, argyrophilic grain dementia, arthritis, asthma, atherosclerosis, atypical hemolytic uremic syndrome
Target
Alternative Names
C1S; complement component 1, s subcomponent; complement C1s subcomponent; C1 esterase; basic proline-rich peptide IB-1; complement component 1 subcomponent s
Entrez Gene ID
716
UniProt ID
P09871

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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