Anti-Human C1S Recombinant Antibody scFv Fragment (5A1) (CAT#: TAB-1326CL-S(P))
This anti-C1s monoclonal antibody is useful for the diagnosis and treatment of disorders associated with an increased activation of the classical complement pathway, in particular autoimmune disorders and neurodegenerative diseases, including neurodegenerative diseases with synapse loss, such as Alzheimer's Disease.
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/1446_A3_2_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/1446_A3_2_selected.jpg
Figure 2 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows distinct positivity in plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/ihc_selected.jpg
(Immunohistochemical staining of human prostate shows distinct positivity in plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/ihc_selected.jpg
Figure 3 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/1184_H1_4_red_green.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/1184_H1_4_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & Cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/151_A11_1_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & Cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18852/151_A11_1_red_green.jpg
Specifications
- Immunogen
- Human C1s enzyme purified from human plasma
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 5A1
- Related Disease
- Autoimmune disorders and neurodegenerative diseases, including neurodegenerative diseases with synapse loss, such as Alzheimer's Disease
Target
- Alternative Names
- C1S; complement component 1, s subcomponent; complement C1s subcomponent; C1 esterase; basic proline-rich peptide IB-1; complement component 1 subcomponent s
- Gene ID
- 716
- UniProt ID
- P09871
Related Resources
Systemic Lupus Erythematosus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 5A1"
See other products for "C1s"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-290-sdAb | Recombinant Anti-Human C1s VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1188z | Mouse Anti-C1S Recombinant Antibody (clone 43C8) | WB, IP, IHC, FuncS | Mouse IgG2a |
| MOB-0274CT | Mouse Anti-C1S Recombinant Antibody (clone 50) | ELISA | Mouse IgG2a |
| HPAB-1493LY | Human Anti-C1S Recombinant Antibody (HPAB-1493LY) | ELISA | Humanized IgG |
| HPAB-N0028-YC | Human Anti-C1s Recombinant Antibody (HPAB-N0028-YC) | ELISA | Humanized IgG |
| MOR-0023-FY | Mouse Anti-C1S Recombinant Antibody (clone M81) | FC, FuncS, IA, IP, WB | Mouse IgG1 |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0088CL | Human Anti-C1S Recombinant Antibody (TAB-0088CL) | ELISA, CMDC, Stim, Hemolysis, Inhib | Humanized Antibody |
| TAB-0088CL-S(P) | Human Anti-C1S Recombinant Antibody; scFv Fragment (TAB-0088CL-S(P)) | ELISA, Stim, Inhib | Humanized scFv |
| TAB-0088CL-F(E) | Human Anti-C1S Recombinant Antibody; Fab Fragment (TAB-0088CL-F(E)) | ELISA, Stim, Inhib | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1326CL | Anti-Human C1S Recombinant Antibody (5A1) | ELISA, Neut | |
| TAB-1327CL | Anti-Human C1S Recombinant Antibody (5C12) | ELISA, Neut | |
| TAB-0087CL-S(P) | Mouse Anti-C1S Recombinant Antibody; scFv Fragment (TAB-0087CL-S(P)) | ELISA, Stim, Inhib | Mouse scFv |
| TAB-1327CL-S(P) | Anti-Human C1S Recombinant Antibody scFv Fragment (5C12) | ELISA, FuncS | |
| TAB-0087CL-F(E) | Mouse Anti-C1S Recombinant Antibody; Fab Fragment (TAB-0087CL-F(E)) | ELISA, Stim, Inhib | Mouse Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-078CQ | Mouse Anti-C1S Recombinant Antibody (clone M241) | WB, Neut, FC, IA, IHC, IHC-Fr, IHC-P | Mouse IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0410 | Hi-Affi™ Rabbit Anti-C1S Recombinant Antibody (clone DS410AB) | WB | Rabbit IgG |
| MOR-0411 | Hi-Affi™ Rabbit Anti-C1S Recombinant Antibody (clone DS411AB) | ELISA | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1493LY-S(P) | Human Anti-C1S Recombinant Antibody; scFv Fragment (HPAB-1493LY-S(P)) | ELISA | Human scFv |
| HPAB-N0028-YC-S(P) | Human Anti-C1s Recombinant Antibody; scFv Fragment (HPAB-N0028-YC-S(P)) | ELISA | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1493LY-F(E) | Human Anti-C1S Recombinant Antibody; Fab Fragment (HPAB-1493LY-F(E)) | ELISA | Humanized Fab |
| HPAB-N0028-YC-F(E) | Human Anti-C1s Recombinant Antibody; Fab Fragment (HPAB-N0028-YC-F(E)) | ELISA | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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