Afuco™ Anti-Human CAV1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-089CL)
Anti-CAV1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a humanized monoclonal antibody developed into a potential anti-prostate cancer therapeutic.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3791/624_H5_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3791/624_H5_2_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3791/630_H5_1_blue_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3791/630_H5_1_blue_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3791/628_H5_1_blue_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3791/628_H5_1_blue_green.jpg
Figure 4 Cerebral cortex
(Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_B_8_5.jpg
(Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_B_8_5.jpg
Figure 5 Lung
(Alveolar cells type I
Staining:High
Intensity: Strong
Quantity:>75%
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_1_4.jpg
(Alveolar cells type I
Staining:High
Intensity: Strong
Quantity:>75%
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_1_4.jpg
Figure 6 Colon
(Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_7_3.jpg
(Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_7_3.jpg
Figure 7 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_8_4.jpg
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_8_4.jpg
Figure 8 Kidney
(Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_7_5.jpg
(Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49326/124801_A_7_5.jpg
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- CAV1; caveolin 1, caveolae protein, 22kDa; CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; caveolin-1; cell growth-inhibiting protein 32
- Gene ID
- 857
- UniProt ID
- A0A024R757
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CAV1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-354-VHH | Recombinant Anti-Human CAV1 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1700z | Mouse Anti-CAV1 Recombinant Antibody (clone 23F5) | WB, ICC, IF | Mouse IgG2b |
| MOB-0332CT | Mouse Anti-CAV1 Recombinant Antibody (clone BU5D2) | ELISA, WB | Mouse IgG2b |
| MRO-0254-CN | Rabbit Anti-CAV1 Recombinant Antibody (clone CBACN-098) | WB, IF, IHC | Rabbit IgG |
| MRO-0255-CN | Mouse Anti-CAV1 Recombinant Antibody (clone 19-D6) | WB, IF, IHC | Mouse IgG1 |
| VS3-WK862 | Rabbit Anti-CAV1 Recombinant Antibody (VS3-WK862) | WB, ELISA | Rabbit IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1487CL | Anti-Human CAV1 Recombinant Antibody (3E2.H5) | FuncS | |
| TAB-1488CL | Anti-Human CAV1 Recombinant Antibody (3E2.1) | FuncS | |
| TAB-1489CL | Anti-Human CAV1 Recombinant Antibody (3H10.6.3.4) | FuncS | |
| TAB-1490CL | Anti-Human CAV1 Recombinant Antibody (1E12C9) | FuncS | |
| TAB-1491CL | Anti-Human CAV1 Recombinant Antibody (1A3F9) | ELISA |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0485 | Hi-Affi™ Rabbit Anti-CAV1 Recombinant Antibody (clone DS485AB) | ICC, IP, WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0087-YC-S(P) | Mouse Anti-CAV1 Recombinant Antibody (clone 3E2); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0088-YC-S(P) | Mouse Anti-CAV1 Recombinant Antibody (clone 1E12); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0089-YC-S(P) | Mouse Anti-CAV1 Recombinant Antibody (clone 1A3); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0087-YC-F(E) | Mouse Anti-CAV1 Recombinant Antibody (clone 3E2); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0088-YC-F(E) | Mouse Anti-CAV1 Recombinant Antibody (clone 1E12); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0089-YC-F(E) | Mouse Anti-CAV1 Recombinant Antibody (clone 1A3); Fab Fragment | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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