The CC-chemokine receptor CCR5 is the major co-receptor for macrophage-tropic (R5) strains, and plays a crucial role in the sexual transmission of HIV-1 (4, 5, 21, 36). T cell line-tropic (X4) viruses use CXCR4 to enter target cells, and usually, but not always, emerge late in disease progression or as a consequence of virus propagation in tissue culture. Anti-CCR5 monoclonal antibodies have also shown the importance of the extracellular loops for viral entry
Figure 1 pro 140 serum concentrations following a single intrawennous injection in HIV-infected invidulas
Provides PRO 140 serum concentrations following a single intravenous injection in HIV-infected individuals,and shows differences between 0.5 mg/kg (rep resented by a square),2 mg/kg (represented by a triangle, and 5 mg/kg (represented by a diamond) amounts.
Figure 2 emax analysis of antiviral data generated with IV and SC PRO 140, measure as Logo change in HIV-1 RNA versus AUC, mg * day/mL
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1134z | Mouse Anti-CCR5 Recombinant Antibody (clone 12B10) | FC, IF, IHC, FuncS | Mouse IgG2a, κ |
MOR-0522 | Hi-Affi™ Rabbit Anti-CCR5 Recombinant Antibody (clone DS522AB) | WB, ELISA, FC, ICC/IF, IP | Rabbit IgG |
PABC-446 | Mouse Anti-CCR5 Recombinant Antibody (clone 4B08) | ELISA | Mouse IgG1, κ |
HPAB-1578WJ | Mouse Anti-CCR5 Recombinant Antibody (clone ST6/34) | ELISA, WB | Mouse IgG |
HPAB-1579WJ | Human Anti-CCR5 Recombinant Antibody (clone ST6) | ELISA, WB | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NABL-078 | Recombinant Anti-mouse Ccr5 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B039(A) | Recombinant Anti-human CCR5 Intrabody [(D-Arg)9] | PCA, WB, FuncS | scFv-(D-Arg)9 |
IAB-B039(G) | Recombinant Anti-human CCR5 Intrabody [+36 GFP] | FACS, ELISA, IF, FuncS | scFv-(+36GFP) |
IAB-B039(T) | Recombinant Anti-human CCR5 Intrabody [Tat] | FACS, ICC, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-10000S | Anti-Human CCR5 Recombinant Antibody | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG4 |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-345 | Mouse Anti-CCR5 Recombinant Antibody (clone RoAb13); scFv Fragment | Block, ELISA, FC | Mouse scFv |
HPAB-0695-YJ-S(P) | Rabbit Anti-CCR5 Recombinant Antibody (ST6); scFv Fragment | ELISA, Block | Rabbit scFv |
HPAB-0696-YJ-S(P) | Human Anti-CCR5 Recombinant Antibody (ST6/34); scFv Fragment | ELISA, Block | Humanized scFv |
HPAB-1578WJ-S(P) | Mouse Anti-CCR5 Recombinant Antibody; scFv Fragment (clone ST6/34) | ELISA, WB | Mouse scFv |
HPAB-1579WJ-S(P) | Human Anti-CCR5 Recombinant Antibody; scFv Fragment (clone ST6) | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1535CL | Mouse Anti-CCR5 Recombinant Antibody (TAB-1535CL) | ELISA, FC | Mouse IgG |
TAB-1536CL | Mouse Anti-CCR5 Recombinant Antibody (TAB-1536CL) | ELISA | Mouse IgG |
TAB-1537CL | Mouse Anti-CCR5 Recombinant Antibody (TAB-1537CL) | ELISA, FuncS | Mouse IgG |
TAB-1538CL | Mouse Anti-CCR5 Recombinant Antibody (TAB-1538CL) | ELISA | Mouse IgG |
TAB-1539CL | Mouse Anti-CCR5 Recombinant Antibody (TAB-1539CL) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1531CL-S(P) | Human Anti-CCR5 Recombinant Antibody; scFv Fragment (TAB-1531CL-S(P)) | FuncS | Human scFv |
TAB-1532CL-S(P) | Human Anti-CCR5 Recombinant Antibody; scFv Fragment (TAB-1532CL-S(P)) | FuncS | Human scFv |
TAB-1533CL-S(P) | Anti-Human CCR5 Recombinant Antibody scFv Fragment (15.186.35) | ELISA, WB | Human antibody |
TAB-1534CL-S(P) | Anti-Human CCR5 Recombinant Antibody scFv Fragment (15.150.11) | ELISA, WB | Human antibody |
TAB-1531CL-F(E) | Human Anti-CCR5 Recombinant Antibody; Fab Fragment (TAB-1531CL-F(E)) | FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-106LC | Recombinant Anti-Human CCR5 Antibody (Fc glycosylation) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-267CQ | Mouse Anti-CCR5 Recombinant Antibody (clone 45523.111) | FC, IHC-P, Neut | Mouse IgG2b |
NEUT-268CQ | Mouse Anti-CCR5 Recombinant Antibody (clone CBL472) | FC, CyTOF, ICC, Neut | Mouse IgG2b |
NEUT-269CQ | Mouse Anti-CCR5 Recombinant Antibody (clone MM0681-7D32) | FC, IHC-P, Neut | Mouse IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0047-YC-F(E) | Human Anti-CCR5 Recombinant Antibody (clone huPR0140); Fab Fragment | Block | Humanized Fab |
HPAB-0131CQ-F(E) | Mouse Anti-CCR5 Recombinant Antibody; Fab Fragment (HPAB-0131CQ-F(E)) | ELISA, FC | Mouse Fab |
PFBC-446 | Mouse Anti-CCR5 Recombinant Antibody (clone 4B08); Fab Fragment | ELISA | Mouse Fab |
HPAB-1038-FY-S(P) | Human Anti-CCR5 Recombinant Antibody (clone 36F11); Fab Fragment | ELISA, FC | Human Fab |
HPAB-0695-YJ-F(E) | Rabbit Anti-CCR5 Recombinant Antibody (ST6); Fab Fragment | ELISA, Block | Rabbit Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-017CN | Mouse Anti-CCR5 Recombinant Antibody (clone PA14) | ELISA, WB, FC | Mouse IgG1 |
NS-017CN-F(E) | Mouse Anti-CCR5 Recombinant Antibody (clone PA14); Fab Fragment | ELISA, WB, FC | Mouse Fab |
NS-017CN-S(P) | Mouse Anti-CCR5 Recombinant Antibody (clone PA14); scFv Fragment | ELISA, WB, FC | Mouse scFv |
There are currently no Customer reviews or questions for HPAB-0047-YC. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.