Anti-Human CD22 Recombinant Antibody (VM1000) (CAT#: TAB-002LC)

Recombinant monoclonal antibody to CD22. VM1000 is a humanized antibody that can be potentially used in the treatment of non-Hodkin's lymphoma, acute lymphocytic leukemia and chronic lymphocytic leukemia.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Tested Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 shows data for the surface binding and internalization analysis on CD22 expressing human lymphoma cells, such as Daudi, RAMOS and RAJI B cell lines by fluorescent activated cell sorting (FACS) of selected clone from VM1000.

Figure 1 shows data for the surface binding and internalization analysis on CD22 expressing human lymphoma cells, such as Daudi, RAMOS and RAJI B cell lines by fluorescent activated cell sorting (FACS) of selected clone from VM1000.

FuncS

Figure 2 show induction of CD22 tyrosine phosphorylation of CD22 present on the surface of the human lymphoma cell line Daudi upon exposure to selected antibodies from VM1000, VM1001, VM1002, VM1003, VM1004, VM1005, VM1006, VM1007, VM1008, VM1009, VM1010, VM1011, VM1012, VM1013, VM1014, and VM1015

Figure 2 show induction of CD22 tyrosine phosphorylation of CD22 present on the surface of the human lymphoma cell line Daudi upon exposure to selected antibodies from VM1000, VM1001, VM1002, VM1003, VM1004, VM1005, VM1006, VM1007, VM1008, VM1009, VM1010, VM1011, VM1012, VM1013, VM1014, and VM1015

FuncS

Figure 3 show induction of CD22 tyrosine phosphorylation of CD22 present on the surface of the human lymphoma cell line Daudi upon exposure to selected antibodies from VM1000, VM1001, VM1002, VM1003, VM1004, VM1005, VM1006, VM1007, VM1008, VM1009, VM1010, VM1011, VM1012, VM1013, VM1014, and VM1015

Figure 3 show induction of CD22 tyrosine phosphorylation of CD22 present on the surface of the human lymphoma cell line Daudi upon exposure to selected antibodies from VM1000, VM1001, VM1002, VM1003, VM1004, VM1005, VM1006, VM1007, VM1008, VM1009, VM1010, VM1011, VM1012, VM1013, VM1014, and VM1015


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • VM1000
  • Applications
  • FC, ELISA, SPR, FuncS
  • Related Disease
  • Non-Hodkin's lymphoma, Acute lymphocytic leukemia, Chronic lymphocytic leukemia

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry and Functional Assay. Please see the Published Data for further information.

Target

  • Alternative Names
  • CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Immunotoxin

CAT Product Name Application Type
AGTO-G077E Anti-CD22 immunotoxin RFB4 (IgG)-PE Cytotoxicity assay, Function study
AGTO-G077D Anti-CD22 immunotoxin RFB4 (IgG)-DT Cytotoxicity assay, Function study
AGTO-G077G Anti-CD22 immunotoxin RFB4 (IgG)-Gel Cytotoxicity assay, Function study
AGTO-G077R Anti-CD22 immunotoxin RFB4 (IgG)-RTA Cytotoxicity assay, Function study
AGTO-L048E anti-CD22 immunotoxin RFB4 (scFv)-PE Cytotoxicity assay, Functional assay

Fab Glycosylation

CAT Product Name Application Type
Gly-001LC Recombinant Anti-Human CD22 Antibody (Fab glycosylation) ELISA, FC Mouse antibody

Fc Glycosylation

CAT Product Name Application Type
Gly-111LC Recombinant Anti-Human CD22 Antibody (Fc glycosylation) ELISA Chimeric antibody (mouse/human)

Blocking Antibody

CAT Product Name Application Type
NEUT-315CQ Rat Anti-CD22 Recombinant Antibody (clone 2D6) Block Rat IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0545 Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB) IP, WB Rabbit IgG

Recombinant Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-176 Afuco™ Anti-CD22 ADCC Recombinant Antibody (Epratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-198 Afuco™ Anti-CD22 ADCC Recombinant Antibody (Inotuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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