Human Anti-CD276 Recombinant Antibody (HPAB-0239-CN) (CAT#: HPAB-0239-CN)
HPAB-0239-CN is a recombinant humanized IgG antibody that specifically targets the human B7-H3 protein. The antibody has been humanized to generate an antibody HPAB-0239-CN, which offers improved therapeutic potential for human treatments. The results of the study showed that the administered Fc-modified hBRCA84D-2 antibody was able to inhibit the tumor growth of HT-1197 bladder cancer cells and A498 kidney cancer cells at all doses.
Specific Inquiry
ELISA
Figure 1 Anti-CD276 Antibody (HPAB-0239-CN) in ELISA
ELISA analysis of HPAB-0239-CN was performed by coating with B7-H3 Protein, Human, Recombinant (His Tag).
The secondary antibody: HRP-Anti-Human IgG (H+L)
WB
Figure 2 Anti-CD276 Antibody (HPAB-0239-CN) in WB
Western blot analysis of HPAB-0239-CN was performed with B7-H3 Protein, Human, Recombinant (His Tag).
HPAB-0239-CN incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing antigen (0.6μg)
DB
Figure 3 Anti-CD276 Antibody (HPAB-0239-CN) in DB
Dot blot analysis of HPAB-0239-CN was performed with B7-H3 Protein, Human, Recombinant (His Tag).
HPAB-0239-CN incubation concentration: 2ng/μL.
NC: Negative control PC: Positive control
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human CD276
- Species Reactivity
- Human
- Applications
- ELISA, FC, IHC
- Related Disease
- Cancer and inflammation
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD276 Molecule; Costimulatory Molecule; CD276 Antigen; B7 Homolog 3; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2
- Gene ID
- 80381
- UniProt ID
- Q5ZPR3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD276"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-117CL | Anti-Human CD276 Recombinant Antibody (MGA271) | ADCC, FuncS | Antibody |
| TAB-424CQ | Anti-Human CD276 Recombinant Antibody (Enoblituzumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-333CQ | Rat Anti-CD276 Recombinant Antibody (clone MJ18) | Block, FC | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0549 | Hi-Affi™ Rabbit Anti-CD276 Recombinant Antibody (clone DS549AB) | WB, IP, FC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0234-CN | Human Anti-CD276 Recombinant Antibody (HPAB-0234-CN) | ELISA, FC, IF | Human IgG |
| HPAB-0236-CN | Mouse Anti-CD276 Recombinant Antibody (HPAB-0236-CN) | IHC, Cyt, Inhib, ELISA, FC | Mouse IgG1, κ |
| HPAB-0237-CN | Mouse Anti-CD276 Recombinant Antibody (HPAB-0237-CN) | IHC, ELISA, FC | Mouse IgG1, κ |
| HPAB-0238-CN | Mouse Anti-CD276 Recombinant Antibody (HPAB-0238-CN) | ELISA, FC, IHC | Mouse IgG1, κ |
| HPAB-0373-FY | Human Anti-CD276 Recombinant Antibody (HPAB-0373-FY) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0234-CN-F(E) | Human Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-0234-CN-F(E)) | ELISA, FC, IF | Human Fab |
| HPAB-0236-CN-F(E) | Mouse Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-0236-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0237-CN-F(E) | Mouse Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-0237-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0238-CN-F(E) | Mouse Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-0238-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0239-CN-F(E) | Human Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-0239-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0422-YC-S(P) | Mouse Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-M0422-YC-S(P)) | Cyt, FuncS | Mouse scFv |
| HPAB-M0423-YC-S(P) | Mouse Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-M0423-YC-S(P)) | Cyt, FuncS | Mouse scFv |
| HPAB-M0424-YC-S(P) | Human Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-M0424-YC-S(P)) | Cyt, FuncS, IHC | Human scFv |
| HPAB-M0425-YC-S(P) | Mouse Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-M0425-YC-S(P)) | Cyt, FuncS | Mouse scFv |
| HPAB-0373-FY-S(P) | Human Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-0373-FY-S(P)) | ELISA | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-424CQ | Afuco™ Anti-CD276 ADCC Recombinant Antibody (Enoblituzumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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