Anti-Human CD28 Recombinant Antibody (HuTN228) (CAT#: TAB-069LC)

HuTN228 is a recombinant monoclonal antibody targeting CD28. It is a humanized antibody with potential applications in transplant rejection treatment. HuTN228 antibodies specifically recognize the CD28 antigen through interactions in the V-region. The IC50 value of HuTN228 is 0.5 g/ml.


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  • Purity:
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 The binding of FITC-labeled MuTN228 to P815/CD28′ cells in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in a flow cytometry competition experiment.

Figure 1 The binding of FITC-labeled MuTN228 to P815/CD28′ cells in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in a flow cytometry competition experiment.

ELISA

Figure 2 ELISA competition assay.

Figure 2 ELISA competition assay.

The binding of biotinylated MuTN228 to sCD28-Fc in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in an ELISA competition experiment.

Figure 3 I¹²⁵ competition assay. The binding of ¹²⁵I labeled MuTN228 to P815/CD28+ cells in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in an ¹²⁵I labeled antibody competition experiment.

Figure 3 I¹²⁵ competition assay. The binding of ¹²⁵I labeled MuTN228 to P815/CD28+ cells in the presence of various amounts of competitor MuTN228 or HuTN228 antibody was analyzed in an ¹²⁵I labeled antibody competition experiment.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • HuTN228
  • Applications
  • ELISA, FC
  • Related Disease
  • Transplant rejection

Applications

  • Application Notes
  • This antibody has been tested for use in Enzyme-linked Immunosorbent Assay and Flow Cytometry. Please see the Published Data for further information.

Target

  • Alternative Names
  • Tp44; CD28

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone HuTN228"

See other products for "CD28"

Chimeric Antibody

CAT Product Name Application Type
TAB-068LC Anti-Human CD28 Recombinant Antibody (ChTN228) ELISA, FC Chimeric antibody (mouse/human)
TAB-068LC-S(P) Anti-Human CD28 Recombinant Antibody scFv Fragment (ChTN228) FC, ELISA Chimeric antibody (mouse/human)
TAB-068LC-F(E) Anti-Human CD28 Recombinant Antibody Fab Fragment (ChTN228) FC, ELISA Chimeric antibody (mouse/human)

Mouse Antibody

CAT Product Name Application Type
PABX-031 Recombinant Mouse Anti-CD28 Antibody (5.11A1) WB, ELISA, FuncS, Activ IgG
PABX-031-F (E) Recombinant Mouse Anti-CD28 Antibody Fab Fragment (5.11A1) WB, ELISA, FuncS Fab

Human Antibody

CAT Product Name Application Type
PABX-031-S (P) Recombinant Mouse Anti-CD28 Antibody scFv Fragment (5.11A1) WB, ELISA, FuncS scFv

Neutralizing Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-335CQ Hamster Anti-CD28 Recombinant Antibody (clone 37.51) IHC-Fr, FC, IP, Block, FuncS Hamster IgG
NEUT-336CQ Mouse Anti-CD28 Recombinant Antibody (clone E18) FC, Costim, Block Mouse IgG2b, κ

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H47 Afuco™ Anti-CD28 ADCC Recombinant Antibody (Lumretuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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