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Hi-Affi™ Rabbit Anti-CD44 Recombinant Antibody (clone DS563AB) (CAT#: MOR-0563)

Recombinant Rabbit anti-CD44 monoclonal antibody for FC, ICC/IF, IHC-Fr, IHC-P, WB, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.


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Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/316/203_H10_1_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/112/if_selected.jpg
Figure 3 IHC staining of human vagina
Figure 3 IHC staining of human vagina
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/316/5_B_2_2_selected.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(Endocrine cells
Staining: High
Intensity: Strong
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Enterocytes
Staining: Medium
Intensity: Strong
Quantity: <25%
Goblet cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity:>75%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_A_9_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_A_8_5.jpg
Figure 6 Skin
Figure 6 Skin
(Cells in basal layer
Staining: High
Intensity: Strong
Quantity:>75%
Cells in spinous layer
Staining: High
Intensity: Strong
Quantity:>75%
Fibrohistiocytic cells
Staining: High
Intensity: Strong
Langerhans cells
Staining: High
Intensity: Strong
Quantity:>75%
Lymphocytes
Staining: High
Intensity: Strong
Melanocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_B_7_1.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5785/16384_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000026508-CD44
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000026508-CD44

Specifications

  • Immunogen
  • Synthetic peptide: TRYVQKGEYRTNPEDIYPS, corresponding to amino acids 153-171 of Human CD44.
  • Host Species
  • Rabbit
  • Derivation
  • Phage display library screening
  • Type
  • Rabbit IgG
  • Species Reactivity
  • Human
  • Clone
  • DS563AB
  • Applications
  • FC, IF, IHC-Fr, IHC-P, WB
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Tissue culture supernatant
  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Format
  • Liquid
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD44 Molecule (Indian Blood Group); Hematopoietic Cell E- And L-Selectin Ligand; GP90 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein 1; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; CD44 Antigen (Homing Function And Indian Blood Group System);Homing Function And Indian Blood Group System; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CD44 Antigen; CSPG8; HCELL; PGP-1; PGP-I; MC56; Pgp1; IN

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CD44"

Humanized Antibody

CAT Product Name Application Type
TAB-727 Anti-CD44 Recombinant Antibody (Bivatuzumab) ELISA, FC, IP, FuncS, IF, Neut, ICC IgG1
TAB-236LC Anti-Human CD44 Recombinant Antibody (huPTA-4621) FuncS Humanized antibody
TAB-236LC-S(P) Anti-Human CD44 Recombinant Antibody scFv Fragment (huPTA-4621) FC Humanized antibody
TAB-236LC-F(E) Anti-Human CD44 Recombinant Antibody Fab Fragment (huPTA-4621) FC Humanized antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-231LC Human Anti-CD44 Recombinant Antibody (TAB-231LC) ELISA Chimeric antibody (mouse/human)
TAB-232LC Human Anti-CD44 Recombinant Antibody (TAB-232LC) ELISA Chimeric antibody (mouse/human)
TAB-235LC Anti-Human CD44 Recombinant Antibody (chPTA-4621) FuncS Chimeric antibody (mouse/human)
TAB-231LC-F(E) Human Anti-CD44 Recombinant Antibody; Fab Fragment (TAB-231LC-F(E)) ELISA Chimeric (mouse/human) Fab
TAB-232LC-F(E) Human Anti-CD44 Recombinant Antibody; Fab Fragment (TAB-232LC-F(E)) ELISA Chimeric (mouse/human) Fab

Mouse Antibody

CAT Product Name Application Type
TAB-237LC Anti-Human CD44 Recombinant Antibody (LGadh01-01) FuncS
TAB-238LC Anti-Human CD44 Recombinant Antibody (LGadh01-02) ELISA
TAB-237LC-S(P) Anti-Human CD44 Recombinant Antibody scFv Fragment (LGadh01-01) ELISA
TAB-238LC-S(P) Anti-Human CD44 Recombinant Antibody scFv Fragment (LGadh01-02) ELISA
TAB-237LC-F(E) Anti-Human CD44 Recombinant Antibody Fab Fragment (LGadh01-01) ELISA

Human Antibody

CAT Product Name Application Type
TAB-239LC Human Anti-CD44 Recombinant Antibody (TAB-239LC) FC Human IgG
TAB-239LC-S(P) Human Anti-CD44 Recombinant Antibody; scFv Fragment (TAB-239LC-S(P)) FC Human scFv
TAB-226LC-F(E) Human Anti-CD44 Recombinant Antibody; Fab Fragment (TAB-226LC-F(E)) WB, ELISA Human Fab
TAB-227LC-F(E) Anti-Human CD44 Recombinant Antibody Fab Fragment (1A9.A6.B9) FC, ELISA Human antibody
TAB-239LC-F(E) Human Anti-CD44 Recombinant Antibody; Fab Fragment (TAB-239LC-F(E)) FC Human Fab

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0101MZ Chicken Anti-CD44 Polyclonal IgY WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-378CQ Rat Anti-CD44 Recombinant Antibody (clone 1M7.8.1) FC, IF, Inhib, IP, WB Rat IgG2b
NEUT-381CQ Human Anti-CD44 Recombinant Antibody (clone Hermes-3) ELISA, FC, IF, IHC, IP, Neut, WB Human IgG1, κ
NEUT-382CQ Rat Anti-CD44 Recombinant Antibody (clone IM7) Block Rat IgG2b
NEUT-383CQ Rat Anti-CD44 Recombinant Antibody (clone KM201), FITC Block, FC, IP, WB, FuncS Rat IgG1, κ
NEUT-384CQ Rat Anti-CD44 Recombinant Antibody (clone KM81) IF, IHC-P, FC, Block Rat IgG2a

Neutralizing Antibody

CAT Product Name Application Type
NEUT-379CQ Mouse Anti-CD44 Recombinant Antibody (clone F10-44-2) WB, Neut, FC, IHC, IHC-Fr, IHC-P, IP, ICC Mouse IgG2a
NEUT-380CQ Rat Anti-CD44 Recombinant Antibody (clone Hermes-1) WB, Neut, ELISA, FC, IF, IHC, IP Rat IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4548 Hi-Affi™ Rabbit Anti-CD44 Recombinant Antibody (clone TH58DS) IF, ICC, FC Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0054-YC-F(E) Mouse Anti-CD44 Recombinant Antibody (clone mH460-16-2); Fab Fragment ELISA, FC, IHC Mouse Fab
HPAB-0055-YC-F(E) Human Anti-CD44 Recombinant Antibody (clone chH460-16-2); Fab Fragment ELISA, FC, IHC Human Fab
HPAB-1055-FY-S(P) Mouse Anti-CD44 Recombinant Antibody; scFv Fragment (HPAB-1055-FY-S(P)) IHC, Inhib, FC Mouse scFv
HPAB-1056-FY-S(P) Mouse Anti-CD44 Recombinant Antibody; scFv Fragment (HPAB-1056-FY-S(P)) IHC, Inhib, FC Mouse scFv
HPAB-1173WJ-F(E) Human Anti-CD44 Recombinant Antibody; Fab Fragment (HPAB-1173WJ-F(E)) ELISA Human Fab

Recombinant Antibody

CAT Product Name Application Type
HPAB-0154-FY Human Anti-CD44 Recombinant Antibody (clone (hu)ARH460-16-2 variant HV2/KV1) Inhib, WB Humanized IgG1
HPAB-0746-FY Human Anti-CD44 Recombinant Antibody (HPAB-0746-FY) ELISA Human IgG
HPAB-0747-FY Human Anti-CD44 Recombinant Antibody (HPAB-0747-FY) ELISA Human IgG
HPAB-1055-FY Mouse Anti-CD44 Recombinant Antibody (HPAB-1055-FY) IP, IHC, Inhib, FC Mouse IgG
HPAB-1056-FY Human Anti-CD44 Recombinant Antibody (HPAB-1056-FY) IHC, Inhib, FC Human IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-727 Afuco™ Anti-CD44 ADCC Recombinant Antibody (Bivatuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0047-YJ-S(P) Mouse Anti-CD44 Recombinant Antibody (clone HI44a); scFv Fragment WB, IF, FC Mouse scFv
HPAB-0746-FY-F(E) Human Anti-CD44 Recombinant Antibody; Fab Fragment (HPAB-0746-FY-F(E)) ELISA Human Fab
HPAB-0747-FY-F(E) Human Anti-CD44 Recombinant Antibody; Fab Fragment (HPAB-0747-FY-F(E)) ELISA Human Fab
HPAB-1055-FY-F(E) Mouse Anti-CD44 Recombinant Antibody; Fab Fragment (HPAB-1055-FY-F(E)) IHC, Inhib, FC Mouse Fab
HPAB-1056-FY-F(E) Mouse Anti-CD44 Recombinant Antibody; Fab Fragment (HPAB-1056-FY-F(E)) IHC, Inhib, FC Mouse Fab

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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