Anti-Human CD47 Recombinant Antibody scFv Fragment (CAT#: TAB-131CL)
Recombinant Humanized monoclonal antibody scFv Fragment expressed in E. coli binding to Human CD47. This is a single-chain antibody fragment (scFv) of murine monoclonal antibody, MABL, which specifically bound to human CD47 (hCD47) and induced apoptosis of the leukemic cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/204_F3_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/204_F3_1_selected.jpg
Figure 2 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows strong cytoplasmic and membranous positivity in urothelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/ihc_selected.jpg
(Immunohistochemical staining of human urinary bladder shows strong cytoplasmic and membranous positivity in urothelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/ihc_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/205_F3_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/205_F3_1_blue_red_green.jpg
Figure 4 Cerebral cortex
(Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_B_8_5.jpg
(Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_B_8_5.jpg
Figure 5 Colon
(Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_8_3.jpg
(Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_8_3.jpg
Figure 6 Testis
(Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_4_6.jpg
(Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_4_6.jpg
Figure 7 Prostate
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_2_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_2_5.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196776-CD47
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196776-CD47
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196776-CD47
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196776-CD47
Specifications
- Derivation
- Humanized
- Type
- scFv fragment
- Species Reactivity
- Human
- Related Disease
- B-cell malignancies
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD47; CD47 molecule; IAP; OA3; MER6; leukocyte surface antigen CD47; CD47 glycoprotein; Rh-related antigen; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; antigenic surface determinant protein OA3; antigen
- Gene ID
- 961
- UniProt ID
- Q08722
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD47"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-278LC | Human Anti-CD47 Recombinant Antibody (TAB-278LC) | Block, FuncS | Human IgG, κ |
| TAB-279LC | Human Anti-CD47 Recombinant Antibody (TAB-279LC) | Block, FuncS | Human IgG, κ |
| TAB-278LC-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (TAB-278LC-S(P)) | ELISA | Human scFv |
| TAB-278LC-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (TAB-278LC-F(E)) | ELISA | Human Fab |
| TAB-279LC-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (TAB-279LC-F(E)) | ELISA | Human Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-280LC | Human Anti-CD47 Recombinant Antibody (TAB-280LC) | ELISA | Humanized antibody |
| TAB-281LC | Human Anti-CD47 Recombinant Antibody (TAB-281LC) | ELISA | Humanized antibody |
| TAB-282LC | Human Anti-CD47 Recombinant Antibody (TAB-282LC) | ELISA | Humanized antibody |
| TAB-283LC | Human Anti-CD47 Recombinant Antibody (TAB-283LC) | ELISA | Humanized antibody |
| TAB-284LC | Human Anti-CD47 Recombinant Antibody (TAB-284LC) | ELISA | Humanized antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-387CQ | Mouse Anti-CD47 Recombinant Antibody (clone CBL377) | Block, FC, CyTOF | Mouse IgG1 |
| NEUT-388CQ | Mouse Anti-CD47 Recombinant Antibody (clone MIAP410) | Block, IF | Mouse IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-389CQ | Rat Anti-CD47 Recombinant Antibody (clone miap301) | FC, FuncS, Neut, WB | Rat IgG2a, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0565 | Hi-Affi™ Rabbit Anti-CD47 Recombinant Antibody (clone DS565AB) | WB, ICC, FC | Rabbit IgG |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0616-CN | Recombinant Dromedary Anti-CD47 Single Domain Antibody (Nb) | ELISA | VHH |
| HPAB-AP496-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (A4) | FC, BL, FuncS | Alpaca VHH |
| HPAB-AP497-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (F2) | FC | Alpaca VHH |
| HPAB-AP498-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (H5) | FC, BL | Alpaca VHH |
| HPAB-AP499-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (H9) | FC, BL | Alpaca VHH |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0834-CN-F(E) | Mouse Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-0834-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0835-CN-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-0835-CN-F(E)) | ELISA, FC, Neut | Chimeric (mouse/human) Fab |
| HPAB-0836-CN-F(E) | Mouse Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-0836-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0837-CN-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-0837-CN-F(E)) | ELISA, FC, Neut | Chimeric (mouse/human) Fab |
| HPAB-0838-CN-F(E) | Mouse Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-0838-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1082LY | Human Anti-CD47 Recombinant Antibody (HPAB-1082LY) | ELISA | Human IgG |
| HPAB-1083LY | Human Anti-CD47 Recombinant Antibody (HPAB-1083LY) | ELISA | Human IgG |
| HPAB-1084LY | Human Anti-CD47 Recombinant Antibody (HPAB-1084LY) | ELISA | Human IgG |
| HPAB-1085LY | Human Anti-CD47 Recombinant Antibody (HPAB-1085LY) | ELISA | Human IgG |
| HPAB-1086LY | Human Anti-CD47 Recombinant Antibody (HPAB-1086LY) | ELISA | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-464 | Mouse Anti-CD47 Recombinant Antibody (clone B6H12.2); scFv Fragment | WB, IP, FC, Neut, IF, IHC | Mouse scFv |
| HPAB-AP035-YC-S(P) | Human Anti-CD47 Recombinant Antibody (clone AB2.05); scFv Fragment | FuncS | Human scFv |
| HPAB-1278WJ-S(P) | Mouse Anti-CD47 Recombinant Antibody (clone MABL-1); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| HPAB-1279WJ-S(P) | Mouse Anti-CD47 Recombinant Antibody (clone MABL-2); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| HPAB-0676YY-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-0676YY-S(P)) | FC, ELISA | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-131CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.