Anti-Human CD52 Recombinant Antibody (CF1D12) (CAT#: TAB-312LC)

This product is a recombinant mouse antibody that recognizes CD52. It exhibits a dose-dependent effect in enhancing T cell responses to antigens in PBMCs. The antibody enhances T cell responses to antigens in people at risk for type 1 diabetes.


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FuncS

Figure 1 CF1D12 enhances responses of T cells in PBMCs to antigens.

Figure 1 CF1D12 enhances responses of T cells in PBMCs to antigens.

IFN-γ spots per ELISpot plate well for PBMCs pre-incubated with either an isotype control antibody or CF1D12 for 1 h at 37°C and subsequently exposed to no antigen, TT or GAD65 in the presence (black bars) or absence (white bars, labelled 'Antibody pre-bound only') of additional antibody.

FuncS

Figure 2 CF1D12 exhibits a dose-dependent effect in enhancing responses of T cells in PBMCs to antigens.

Figure 2 CF1D12 exhibits a dose-dependent effect in enhancing responses of T cells in PBMCs to antigens.

IFN-γ spots per ELISpot plate well for PBMCs pre-incubated with CF1D12 for 1 h at 37°C and subsequently exposed to TT in the presence (black bars) or absence (white bars, labelled 'Antibody pre-bound') of additional CF 1 D 12 antibody.

FuncS

Figure 3 CF1D12 enhances T cell response to antigens in people at risk for type 1 diabetes.

Figure 3 CF1D12 enhances T cell response to antigens in people at risk for type 1 diabetes.

IFN-γ spots per ELISpot plate well for PBMCs incubated with isotype control antibody or CF 1 D 12 in the presence of no antigen, TT or GAD65.


Specifications

  • Host Species
  • Mouse
  • Specificity
  • Human
  • Clone
  • CF1D12
  • Applications
  • FuncS
  • Related Disease
  • Autoimmune disease

Applications

  • Application Notes
  • This antibody has been reported for use in Functional Assay.

Target

  • Alternative Names
  • CDW52; CD52

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Chimeric Antibody

Fab Glycosylation

CAT Product Name Application Type
Gly-038LC Recombinant Anti-Human CD52 Antibody (Fab glycosylation) ELISA Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0568 Hi-Affi™ Rabbit Anti-CD52 Recombinant Antibody (clone DS568AB) WB, IP Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-469CQ Afuco™ Anti-CD52 ADCC Recombinant Antibody (Tamtuvetmab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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