Anti-Human CD81 Recombinant Antibody (CAT#: TAB-142CL)
Recombinant monoclonal antibody expressed in CHO binding to Human CD81. This is a novel anti-CD81 mAb generated by genetic immunization efficiently blocks HCV spread and dissemination. This antibody will be useful to further unravel the role of virus-host interactions during HCV entry and cell-cell transmission. Furthermore, this antibody may be of interest for the development of antivirals for prevention and treatment of HCV infection.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7234/10_B9_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7234/10_B9_2_selected.jpg
Figure 2 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_A_6_6_selected.jpg
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_A_6_6_selected.jpg
Figure 3 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_B_8_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_B_8_5.jpg
Figure 4 Testis
(Peritubular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Sertoli cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_A_5_6.jpg
(Peritubular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Sertoli cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_A_5_6.jpg
Figure 5 Endometrium
(Cells in endometrial stroma
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_B_3_3.jpg
(Cells in endometrial stroma
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2507/6520_B_3_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110651-CD81
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110651-CD81
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110651-CD81
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110651-CD81
Specifications
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Hepatitis C viral infection
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- CD81; CD81 molecule; S5.7; CVID6; TAPA1; TSPAN28; CD81 antigen; tspan-28; tetraspanin-28; 26 kDa cell surface protein TAPA-1; CD81 antigen (target of antiproliferative antibody 1)
- Gene ID
- 975
- UniProt ID
- E9PJK1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD81"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-036 | Mouse Anti-CD81 Recombinant Antibody (clone K04); Fab Fragment | WB, Block, FuncS | Mouse Fab |
| PFBL-425 | Mouse Anti-CD81 Recombinant Antibody (clone K13); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
| HPAB-0139-FY-F(E) | Human Anti-CD81 Recombinant Antibody (clone 002-A07 S115N); Fab Fragment | Inhib | Human Fab |
| HPAB-0908-YJ-F(E) | Mouse Anti-CD81 Recombinant Antibody; Fab Fragment (HPAB-0908-YJ-F(E)) | ELISA, FC, Inhib | Mouse Fab |
| MOB-164YJL-F(E) | Human Anti-CD81 Recombinant Antibody (clone CBC083); Bivalent Fab Fragment | ELISA, FC | Human Bivalent Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-348LC | Human Anti-CD81 Recombinant Antibody (TAB-348LC) | ELISA | Human IgG4 |
| TAB-349LC | Human Anti-CD81 Recombinant Antibody (TAB-349LC) | ELISA | Human IgG4 |
| TAB-348LC-S(P) | Human Anti-CD81 Recombinant Antibody; scFv Fragment (TAB-348LC-S(P)) | ELISA | Human scFv |
| TAB-349LC-S(P) | Human Anti-CD81 Recombinant Antibody; scFv Fragment (TAB-349LC-S(P)) | ELISA | Human scFv |
| TAB-348LC-F(E) | Human Anti-CD81 Recombinant Antibody; Fab Fragment (TAB-348LC-F(E)) | ELISA | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1539MZ | Recombinant Mouse Anti-Human CD81 Antibody (clone N49), PE-Conjugated | FC, FuncS, ICC, IHC-P, IP, WB | Mouse antibody |
| PABC-257 | Mouse Anti-CD81 Recombinant Antibody (clone Ab4) | ELISA, FC | Mouse IgG |
| PABC-258 | Mouse Anti-CD81 Recombinant Antibody (clone Ab5) | ELISA, FC | Mouse IgG |
| PABC-259 | Mouse Anti-CD81 Recombinant Antibody (clone Ab10) | ELISA, FC | Mouse IgG |
| ZG-0596J | Rabbit Anti-CD81 Recombinant Antibody (clone 9F7) | ELISA, WB, IHC, FC | Rabbit IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-417CQ | Hamster Anti-CD81 Recombinant Antibody (clone 2F7) | Neut, FC, IHC, IHC-Fr, IP, ICC | Hamster IgG3, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-418CQ | Hamster Anti-Cd81 Recombinant Antibody (clone YC081), Biotin | FC, IHC-Fr, IP, Block | Hamster IgG3, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0584 | Hi-Affi™ Rabbit Anti-CD81 Recombinant Antibody (clone DS584AB) | WB, ICC | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0139-FY-S(P) | Human Anti-CD81 Recombinant Antibody (clone 002-A07 S115N); scFv Fragment | Inhib | Human scFv |
| PSBC-257 | Mouse Anti-CD81 Recombinant Antibody (clone Ab4); scFv Fragment | ELISA, FC | Mouse scFv |
| PSBC-258 | Mouse Anti-CD81 Recombinant Antibody (clone Ab5); scFv Fragment | ELISA, FC | Mouse scFv |
| PSBC-259 | Mouse Anti-CD81 Recombinant Antibody (clone Ab10); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0908-YJ-S(P) | Mouse Anti-CD81 Recombinant Antibody; scFv Fragment (HPAB-0908-YJ-S(P)) | ELISA, FC, Inhib | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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