Afuco™ Anti-Human CDH5 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-145CL)
Anti-CDH5 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies are humanized antibodies directed that react with human VE-cadherin for use in a human using to inhibit angiogenesis, inhibit tumor metastasis, or treat cell proliferative disorders.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75875/1842_A1_68_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm, nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75875/1842_A1_68_selected.jpg
Figure 2 IHC staining of human vagina
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in superficial layers of squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/ihc_selected.jpg
(Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in superficial layers of squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_B_7_5.jpg
Figure 4 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_8_5.jpg
Figure 7 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_4_6.jpg
Figure 8 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28366/66242_A_9_8.jpg
Figure 9 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179776-CDH5
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179776-CDH5
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- 95% by HPLC
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- CDH5; cadherin 5, type 2 (vascular endothelium); 7B4; CD144; cadherin-5; 7B4 antigen; VE-cadherin; cd144 antigen; endothelial-specific cadherin; vascular endothelial cadherin; cadherin 5, type 2, VE-cadherin (vascular epithelium)
- Gene ID
- 1003
- UniProt ID
- P33151
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CDH5"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1657z | Mouse Anti-CDH5 Recombinant Antibody (clone 24B9) | WB, FC, ICC, IF, IHC, IP, FuncS | Mouse IgG2a |
| ZG-0169C | Mouse Anti-CDH5 Recombinant Antibody (clone 3G8) | IHC-P, IF | Mouse IgG |
| ZG-0170C | Mouse Anti-CDH5 Recombinant Antibody (clone 8E5) | IHC-P, IF | Mouse IgG |
| VS3-WK1374 | Mouse Anti-CDH5 Recombinant Antibody (clone ABT-MCDH) | IHC-P, WB | Mouse IgG1, κ |
| VS3-WK1375 | Mouse Anti-CDH5 Recombinant Antibody (clone PT1718) | IHC-P, WB, IF | Mouse IgG1, κ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-283CQ | Anti-Mouse Cdh5 Recombinant Antibody (E4B9) | FuncS | |
| TAB-283CQ-S(P) | Anti-Mouse Cdh5 Recombinant Antibody scFv Fragment (E4B9) | ELISA, WB, IF | |
| TAB-283CQ-F(E) | Anti-Mouse Cdh5 Recombinant Antibody Fab Fragment (E4B9) | ELISA, WB, IF |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-449CQ | Mouse Anti-CDH5 Recombinant Antibody (VMC176) | Inhib, WB, IP | Mouse IgG2a |
| NEUT-450CQ | Rat Anti-Cdh5 Recombinant Antibody (clone BV13) | FC, WB, IF, Block | Rat IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4075 | Hi-Affi™ Rabbit Anti-CDH5 Recombinant Antibody (clone SI142DS) | IHC-P | Rabbit IgG |
| MOR-4076 | Hi-Affi™ Rabbit Anti-CDH5 Recombinant Antibody (clone SI143DS) | ELISA, WB | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-1016LC | Mouse Anti-Cdh5 Recombinant Antibody (clone 10G4) | FC |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-145CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.