Recombinant Mouse Antibody (MFE-23) is capable of binding to CEA, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 Characterization of scFv'-fragments targeting EGFR- or CEA-expressing tumor cells.
Flow cytometry analysis of binding of the two scFv fragments to A549 cells.
Mack, K., Rüger, R., Fellermeier, S., Seifert, O., & Kontermann, R. E. (2012). Dual targeting of tumor cells with bispecific single-chain Fv-immunoliposomes. Antibodies, 1(2), 199-214.
Figure 2 ELISA analyzing the binding of monospecific ILs (hu225-IL, MFE23-IL), dual-targeted immunoliposomes (dt-ILs) as well as non-targeted liposomes (nt) to immobilized CEA and detection of bound liposomes by incubation with EGFR-Fc and an anti-Fc antibody.
Only the dt-ILs caused a signal confirming bispecificity.
Mack, K., Rüger, R., Fellermeier, S., Seifert, O., & Kontermann, R. E. (2012). Dual targeting of tumor cells with bispecific single-chain Fv-immunoliposomes. Antibodies, 1(2), 199-214.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-038 | Mouse Anti-CEA Recombinant Antibody (clone T84.66); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
HPAB-0569-CN-F(E) | Mouse Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0569-CN-F(E)) | ELISA, FC | Mouse Fab |
HPAB-0570-CN-F(E) | Human Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0570-CN-F(E)) | ELISA, FC | Humanized Fab |
HPAB-0571-CN-F(E) | Human Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0571-CN-F(E)) | ELISA, FC | Human Fab |
HPAB-0533-YJ-F(E) | Human Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0533-YJ-F(E)) | ELISA, IF, WB, FucnS | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0569-CN | Mouse Anti-CEA Recombinant Antibody (HPAB-0569-CN) | ELISA, FC | Mouse IgG |
HPAB-0570-CN | Human Anti-CEA Recombinant Antibody (HPAB-0570-CN) | ELISA, FC | Humanized IgG |
HPAB-0571-CN | Human Anti-CEA Recombinant Antibody (HPAB-0571-CN) | ELISA, FC | Chimeric (mouse/human) IgG1, κ |
FAMAB-0059YC | Mouse Anti-CEA Recombinant Antibody (clone 2-18) | IF, FuncS | Mouse IgG1, κ |
FAMAB-0060YC | Human Anti-CEA Recombinant Antibody (clone ch2-18) | IF, FuncS | Chimeric (mouse/human) IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0052CQ-S(P) | Mouse Anti-CEA Recombinant Antibody (clone CEA 66-E3); scFv Fragment | ELISA, WB | Mouse scFv |
FAMAB-0053CQ-S(P) | Mouse Anti-CEA Recombinant Antibody (clone CEA 79); scFv Fragment | ELISA, WB, IP | Mouse scFv |
FAMAB-0054CQ-S(P) | Mouse Anti-CEA Recombinant Antibody (clone mAb 8019); scFv Fragment | ELISA | Mouse scFv |
HPAB-0539-WJ-S(P) | Mouse Anti-CEA Recombinant Antibody (clone COL-1); scFv Fragment | ELISA | Mouse scFv |
HPAB-0540-WJ-S(P) | Human Anti-CEA Recombinant Antibody (clone HuCOL-1); scFv Fragment | ELISA | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP500-YC | Recombinant Camel Anti-CEA Single Domain Antibody (ASEAN-1) | ELISA | Camel VHH |
HPAB-1210WJ | Recombinant Dromedary Anti-CEA Single Domain Antibody (CEA1) | ELISA | Dromedary VHH |
HPAB-1211WJ | Recombinant Dromedary Anti-CEA Single Domain Antibody (CEA72) | ELISA | Dromedary VHH |
HPAB-0698-YJ-VHH | Camelid Anti-CEA Recombinant Single Domain Antibody (C17) | ELISA, FC, In vivo staining | Camelid VHH |
HPAB-0699-YJ-VHH | Camelid Anti-CEA Recombinant Single Domain Antibody (C43) | ELISA, FC, In vivo staining | Camelid VHH |
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