Afuco™ Anti-Human CEACAM1 ADCC Recombinant Antibody (CM-24), ADCC Enhanced (CAT#: AFC-147CL)
Anti-CEACAM1 ADCC Enhanced Antibody (CM-24) is an ADCC enhanced antibody produced by our Afuco™ platform. CM-24 is a Phase 1, first-in-class humanized anti CEACAM1 monoclonal antibody that inhibits the immunosuppressive effect of CEAC AM1, leading to an enhanced anti-tumor immune response of T and NK cells.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Enterocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_8_3.jpg
(Enterocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_8_3.jpg
Figure 2 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_9_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_9_5.jpg
Figure 3 RNA cell line category: Group enriched (CAPAN-2, Hep G2, OE19, RT4, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000079385-CEACAM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000079385-CEACAM1
Figure 3 RNA cell line category: Group enriched (CAPAN-2, Hep G2, OE19, RT4, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000079385-CEACAM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000079385-CEACAM1
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; BGP1; BGPI; carcinoembryonic antigen-related cell adhesion molecule 1; antigen CD66; CD66a antigen
- Gene ID
- 634
- UniProt ID
- P13688
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CEACAM1"
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-014-F(E) | Anti-Human CEA Recombinant Antibody Fab Fragment (Arcitumomab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | Fab' - G1 |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-156CL | Human Anti-CEACAM1 Recombinant Antibody (TAB-156CL) | ELISA | Human IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-439LC | Human Anti-CEACAM1 Recombinant Antibody (TAB-439LC) | ELISA, FC, IF | Human IgG |
| TAB-439LC-S(P) | Human Anti-CEACAM1 Recombinant Antibody; scFv Fragment (TAB-439LC-S(P)) | IF, FC, ELISA | Human scFv |
| TAB-439LC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (TAB-439LC-F(E)) | IF, FC, ELISA | Human Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-443LC | Human Anti-CEACAM1 Recombinant Antibody (TAB-443LC) | Block, Cyt, ELISA, FC, FuncS | Chimeric (Mouse/Human) IgG1, κ |
| TAB-443LC-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (TAB-443LC-S(P)) | FC, SPR, IHC, ELISA | Mouse scFv |
| TAB-443LC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (TAB-443LC-F(E)) | FC, SPR, IHC, ELISA | Chimeric (Mouse/Human) Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-453CQ | Mouse Anti-Ceacam1 Recombinant Antibody (clone MAb-CC1) | FC, WB, IP, IHC, ELISA, Block | Mouse IgG1, κ |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-454CQ | Mouse Anti-Ceacam1 Recombinant Antibody (clone CC1) | WB, Neut, FC, FuncS, IHC, IHC-Fr, IHC-P, IP | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0648 | Hi-Affi™ Rabbit Anti-CEACAM1 Recombinant Antibody (clone DS648AB) | IHC-P, WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0470-CN | Mouse Anti-CEACAM1 Recombinant Antibody (HPAB-0470-CN) | ELISA, FC | Mouse IgG |
| HPAB-0471-CN | Mouse Anti-CEACAM1 Recombinant Antibody (clone 18-20) | ELISA, FC | Mouse IgG |
| HPAB-0472-CN | Mouse Anti-CEACAM1 Recombinant Antibody (clone 6G5J) | ELISA, FC | Mouse IgG |
| HPAB-0372-YC | Human Anti-CEACAM1 Recombinant Antibody (HPAB-0372-YC) | ELISA, FC, Activ | Humanized IgG |
| FAMAB-1640CQ | Rat Anti-CEACAM1 Recombinant Antibody (clone YTH 71.3) | FC, IHC-Fr | Rat IgG2a |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0470-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (HPAB-0470-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0471-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (clone 18-20) | ELISA, FC | Mouse scFv |
| HPAB-0472-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (clone 6G5J) | ELISA, FC | Mouse scFv |
| HPAB-0372-YC-S(P) | Human Anti-CEACAM1 Recombinant Antibody; scFv Fragment (HPAB-0372-YC-S(P)) | ELISA, FC, Activ | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0470-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (HPAB-0470-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0471-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (clone 18-20) | ELISA, FC | Mouse Fab |
| HPAB-0472-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (clone 6G5J) | ELISA, FC | Mouse Fab |
| HPAB-0372-YC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (HPAB-0372-YC-F(E)) | ELISA, FC, Activ | Humanized Fab |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0572CQ | Rat Anti-CEACAM1 Recombinant Antibody (clone YTH71.3) | ELISA | Rat IgG2a |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0517 | PE-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0518 | APC-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0519 | FITC-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0520 | B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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