Recombinant Mouse Antibody (mAb16) is capable of binding to CPV, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 Antigenic analysis of capsids prepared as infectious viruses or expressed as empty capsids from expression plasmids.
(B) ELISA results with CPV-d, A300D, G299E, and K387A and a subset of the MAbs shown in panel A. As shown previously, the filled squares indicate that the level of reaction was similar to that seen for CPV-d, hatched squares indicate ,10% the level of reaction to CPV-d at a dilution at which the reaction with CPV-d is .90% saturating, and open squares indicate no reaction
at any antibody dilution.
Parker, J. S., & Parrish, C. R. (1997). Canine parvovirus host range is determined by the specific conformation of an additional region of the capsid. Journal of Virology, 71(12), 9214-9222.
Figure 2 The neutralization of (A) CPV-2 and (B) FPV infectivity by various amounts of the IgGs of the 8 different MAb tested here.
The IgGs were added to 10,000 TCID₅₀ of each virus at concentrations between 0 and 100 nM, incubated for 1 h at 37 °C, then the surviving virus was diluted and tested for surviving TCID50 in
CRFK cells. The results are shown as the surviving infectivity in each culture compared to the titer of the control virus. Bars show the standard error of the mean, comparing the results of 3 separate experiments done on separate days.
Nelson, C. D., Palermo, L. M., Hafenstein, S. L., & Parrish, C. R. (2007). Different mechanisms of antibody-mediated neutralization of parvoviruses revealed using the Fab fragments of monoclonal antibodies. Virology, 361(2), 283-293.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
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• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-237 | Recombinant Anti-CPV Antibody | ELISA, WB, FC, FuncS | IgG |
PABL-435 | Recombinant Mouse Anti-CPV Antibody (730.1.4) | WB, IF, FuncS | IgG |
MOB-0195MZ | Recombinant Mouse Anti-Canine Parvovirus Antibody (clone 8H8) | ELISA, LFIA | Mouse antibody |
PABC-482 | Recombinant Rat Anti-CPV Antibody (MAb E) | ELISA, Neut | Rat IgG1, κ |
HPAB-A1274-YJ | Cat Anti-CPV Recombinant Antibody (clone CPV) | WB, ELISA, Neut, Inhib | Cat IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-140 | Recombinant Mouse Anti-CPV Antibody Fab Fragment (mAb16) | Neut | Fab |
PFBW-141 | Recombinant Mouse Anti-CPV Antibody Fab Fragment (mAb15) | Neut | Fab |
PFBW-142 | Recombinant Mouse Anti-CPV Antibody Fab Fragment (mAb8) | Neut | Fab |
PFBW-143 | Recombinant Mouse Anti-CPV Antibody Fab Fragment (mAb6) | Neut | Fab |
PFBW-145 | Recombinant Mouse Anti-CPV Antibody Fab Fragment (mAb14) | Neut | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBW-140 | Recombinant Mouse Anti-CPV Antibody scFv Fragment (mAb16) | Neut | scFv |
PSBW-141 | Recombinant Mouse Anti-CPV Antibody scFv Fragment (mAb15) | Neut | scFv |
PSBW-142 | Recombinant Mouse Anti-CPV Antibody scFv Fragment (mAb8) | Neut | scFv |
PSBW-143 | Recombinant Mouse Anti-CPV Antibody scFv Fragment (mAb6) | Neut | scFv |
PFBC-482 | Recombinant Rat Anti-CPV Antibody Fab Fragment (MAb E) | ELISA, Neut | Rat Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-023 | Recombinant Mouse Anti-CPV Antibody (FabB) | WB, ELISA, FuncS | IgG |
PABX-023-S (P) | Recombinant Mouse Anti-CPV Antibody scFv Fragment (FabB) | WB, ELISA, FuncS | scFv |
PABX-023-F (E) | Recombinant Mouse Anti-CPV Antibody Fab Fragment (FabB) | WB, ELISA, FuncS | Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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