Anti-Mouse CSF1R Recombinant Antibody (AFS98) (CAT#: TAB-079MZ)
Recombinant monoclonal antibody to CSF-1R, AFS98, is a rat monoclonal antibody intended for the prophylaxis and treatment of related disease.
Specific Inquiry
FC
Figure 1 Representative dot plots and quantification of the F4/80+ Ly6C- and CSF1R+ of F4/80+ immune cell infiltrates of WT and Csf1–/– MC38 tumors derived from WT mice at day 21.
Graphs show mean ± SEM of data from at least 3 independent experiments or 5 to 10 individual mice per group.
Gyori, D., Lim, E. L., Grant, F. M., Spensberger, D., Roychoudhuri, R., Shuttleworth, S. J., ... & Hawkins, P. T. (2018). Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy. JCI insight, 3(11).
Specifications
- Host Species
- Rat
- Specificity
- Mouse
- Clone
- AFS98
- Applications
- FC
Applications
- Application Notes
- The CSF1R antibody has been reported in applications of Flow Cytometry. TAMs were isolated from other leukocytes by positive selection for CD115 (anti-mouse CD115-PE, clone AFS98, Biolegend) used at a 1:200 dilution in FACS buffer and incubated at 4°C for 30 minutes. After washing, the cells were incubated with anti-PE microbeads (Miltenyi Biotec) at a 1:10 dilution in FACS buffer at 4°C for a further 20 minutes.
Target
- Alternative Names
- Fms; Fim2; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; AI323359
- Gene ID
- 12978
- UniProt ID
- P09581
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1863z | Mouse Anti-CSF1R Recombinant Antibody (clone 32G11) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2b |
| PABL-055 | Human Anti-CSF1R Recombinant Antibody (clone RG7155) | FC, FuncS | |
| HPAB-0073-LS | Mouse Anti-CSF1R Recombinant Antibody (HPAB-0073-LS) | Block | Mouse IgG4, κ |
| HPAB-0074-LS | Human Anti-CSF1R Recombinant Antibody (HPAB-0074-LS) | Block | Human IgG |
| HPAB-0075-LS | Mouse Anti-CSF1R Recombinant Antibody (HPAB-0075-LS) | ELISA, Inhib | Mouse IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H23 | Anti-Human CSF1R Recombinant Antibody (Emactuzumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
| TAB-076MZ | Human Anti-CSF1R Recombinant Antibody (TAB-076MZ) | WB | Human IgG4 |
| TAB-078MZ | Human Anti-CSF1R Recombinant Antibody (TAB-078MZ) | ELISA | Humanized IgG |
| TAB-076MZ-F(E) | Human Anti-CSF1R Recombinant Antibody; Fab Fragment (TAB-076MZ-F(E)) | WB | Humanized Fab |
| TAB-078MZ-F(E) | Human Anti-CSF1R Recombinant Antibody; Fab Fragment (TAB-078MZ-F(E)) | ELISA | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-178CL | Afuco™ Anti-CSF1R Recombinant Antibody (AFC-178CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
| AFC-TAB-H23 | Afuco™ Anti-CSF1R ADCC Recombinant Antibody (Emactuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-011ML | Afuco™ Anti-CSF1R ADCC Recombinant Antibody (Cabiralizumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-077MZ | Mouse Anti-CSF1R Recombinant Antibody (TAB-077MZ) | ELISA | Mouse IgG2a, κ |
| TAB-077MZ-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (TAB-077MZ-S(P)) | ELISA | Mouse scFv |
| TAB-077MZ-F(E) | Mouse Anti-CSF1R Recombinant Antibody; Fab Fragment (TAB-077MZ-F(E)) | ELISA | Mouse Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-508CQ | Mouse Anti-CSF1R Recombinant Antibody (clone CBL141) | Neut, WB | Mouse IgG1 |
| NEUT-509CQ | Mouse Anti-CSF1R Recombinant Antibody (clone CBL809) | WB, Neut | Mouse IgG1 |
| NEUT-510CQ | Mouse Anti-CSF1R Recombinant Antibody (clone MM0467-5V36) | WB, Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0825 | Hi-Affi™ Rabbit Anti-CSF1R Recombinant Antibody (clone DS825AB) | ELISA | Rabbit IgG |
| MOR-4112 | Hi-Affi™ Rabbit Anti-CSF1R Recombinant Antibody (clone SI183DS) | ELISA | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0574-CN-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0574-CN-S(P)) | ELISA, Block | Mouse scFv |
| HPAB-0575-CN-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0575-CN-S(P)) | ELISA, Block | Mouse scFv |
| HPAB-0576-CN-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0576-CN-S(P)) | ELISA, Block | Humanized scFv |
| HPAB-0577-CN-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0577-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0579-CN-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0579-CN-S(P)) | ELISA, FC, Neut | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0073-LS-F(E) | Mouse Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0073-LS-F(E)) | Block | Mouse Fab |
| HPAB-0074-LS-F(E) | Human Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0074-LS-F(E)) | Block | Human Fab |
| HPAB-0075-LS-F(E) | Mouse Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0075-LS-F(E)) | ELISA, Inhib | Mouse Fab |
| HPAB-0076-LS-F(E) | Mouse Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0076-LS-F(E)) | ELISA, Inhib | Mouse Fab |
| HPAB-0077-LS-F(E) | Human Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0077-LS-F(E)) | ELISA, Inhib | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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