Afuco™ Anti-Human CYR61 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-194CL)
Anti-CYR61 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an antibody againsts human CCN1, useful for the treatment of various cancers, like breast cancer, primary glioma, bladder papilloma, colon adenocarcinoma, melanoma, medulloblastoma, pediatric tumors, fibrosarcoma, ovarian cancer, pancreatic cancer or prostate cancer.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human cervix, uterine
(Immunohistochemical staining of human cervix, uterine shows cytolasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_B_8_3_selected.jpg
(Immunohistochemical staining of human cervix, uterine shows cytolasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_B_8_3_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_B_9_5.jpg
Figure 3 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_8_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_7_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_7_4.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_7_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_7_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_6_6.jpg
Figure 7 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_9_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29853/68976_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, EFO-21, SiHa, TIME, U-251 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000142871-CYR61
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000142871-CYR61
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- 4 °C, -20°C if preferred
Target
- Alternative Names
- CYR61; cysteine-rich, angiogenic inducer, 61; CCN1; GIG1; IGFBP10; protein CYR61; IBP-10; IGFBP-10; CCN family member 1; IGF-binding protein 10; cysteine-rich, anigogenic inducer, 61; cysteine-rich heparin-binding protein 61; insulin-like growth factor-binding protein 10
- Gene ID
- 3491
- UniProt ID
- O00622
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3268z | Mouse Anti-CYR61 Recombinant Antibody (clone 35D2) | WB, ELISA, IHC | Mouse IgG1 |
| MOB-0362CT | Recombinant Mouse anti-Human CYR61 Monoclonal antibody (4I4) | ELISA, ICC/IF, IHC-P, WB |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1506CL | Mouse Anti-Human CYR61 Recombinant Antibody | IHC, Block, ELISA | |
| TAB-1506CL-S(P) | Anti-Human CYR61 Recombinant Antibody scFv Fragment | IHC, Block, ELISA | |
| TAB-1506CL-F(E) | Anti-Human CYR61 Recombinant Antibody Fab Fragment | IHC, Block, ELISA |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1507CL | Human Anti-CYR61 Recombinant Antibody (TAB-1507CL) | ELISA, FC | Human IgG1 |
| TAB-1507CL-S(P) | Human Anti-CYR61 Recombinant Antibody; scFv Fragment (TAB-1507CL-S(P)) | ELISA, FC | Human scFv |
| TAB-1507CL-F(E) | Human Anti-CYR61 Recombinant Antibody; Fab Fragment (TAB-1507CL-F(E)) | ELISA, FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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