Rat Anti-Cd70 Recombinant Antibody (clone FR70) (CAT#: NEUT-406CQ)
This antibody is a rat monoclonal antibody that binds specifically to mouse CD70, and it can neutralize the bioactivity of mouse CD70.
Specific Inquiry
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
Figure 3 RNA cell line category: Cell line enhanced (SiHa, THP-1, U-251 MG, U-266/70, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
Specifications
- Host Species
- Rat
- Type
- Rat IgG2b, κ
- Specificity
- Mouse Cd70
- Species Reactivity
- Mouse
- Clone
- FR70
- Applications
- FC, FuncS, Neut, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD70"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-335LC | Human Anti-CD70 Recombinant Antibody (TAB-335LC) | ELISA | Humanized IgG1, κ |
| TAB-335LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-335LC-F(E)) | ELISA | Humanized Fab |
| TAB-342LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-342LC-F(E)) | FC | Humanized Fab |
| TAB-343LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-343LC-F(E)) | FC | Humanized Fab |
| TAB-344LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-344LC-F(E)) | FC | Humanized Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-336LC-S(P) | Anti-Human CD70 Recombinant Antibody scFv Fragment (Mb VLVH) | FC, ELISA | Human antibody |
| TAB-337LC-S(P) | Anti-Human CD70 Recombinant Antibody scFv Fragment (Mb VHVL) | FC, ELISA | Human antibody |
| TAB-338LC-S(P) | Anti-Human CD70 Recombinant Antibody scFv Fragment (VL-5-VH) | FC, ELISA | Human antibody |
| TAB-339LC-S(P) | Anti-Human CD70 Recombinant Antibody scFv Fragment (VH-5-VL) | FC, ELISA | Human antibody |
| TAB-340LC-S(P) | Anti-Human CD70 Recombinant Antibody scFv Fragment (VL-8-VH) | FC, ELISA | Human antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-403CQ | Rat Anti-Cd70 Recombinant Antibody (clone 9G24) | ELISA, Neut | Rat IgG1 |
| NEUT-405CQ | Rat Anti-Cd70 Recombinant Antibody (clone CBL684) | ELISA, Neut | Rat IgG1 |
| NEUT-407CQ | Rat Anti-Cd70 Recombinant Antibody (clone CBL856) | ELISA, Neut | Rat IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-404CQ | Rat Anti-Cd70 Recombinant Antibody (clone MAB0825) | Block, FC, Inhib, IP | Rat IgG2 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0487-YC | Rat Anti-CD70 Recombinant Antibody (clone 4F2-12) | FC | Rat IgG2a, κ |
| HPAB-AP584-YC | Mouse Anti-CD70 Recombinant Antibody (clone m1F6) | FC, ADCC, CDC, FuncS | Mouse IgG |
| HPAB-AP585-YC | Human Anti-CD70 Recombinant Antibody (clone c1F6) | FC, ADCC, CDC, FuncS | Chimeric (mouse/human) IgG |
| HPAB-AP586-YC | Human Anti-CD70 Recombinant Antibody (clone h1F6-HHLA) | FC, ADCC, CDC, FuncS | Humanized (mouse/human) IgG |
| HPAB-AP587-YC | Human Anti-CD70 Recombinant Antibody (clone h1F6-HELA) | FC, ADCC, CDC, FuncS | Humanized (mouse/human) IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0487-YC-F(E) | Rat Anti-CD70 Recombinant Antibody (clone 4F2-12); Fab Fragment | FC | Rat Fab |
| HPAB-AP584-YC-F(E) | Mouse Anti-CD70 Recombinant Antibody (clone m1F6); Fab Fragment | FC, ADCC, CDC, FuncS | Mouse Fab |
| HPAB-AP585-YC-F(E) | Human Anti-CD70 Recombinant Antibody (clone c1F6); Fab Fragment | FC, ADCC, CDC, FuncS | Chimeric (mouse/human) Fab |
| HPAB-AP586-YC-F(E) | Human Anti-CD70 Recombinant Antibody (clone h1F6-HHLA); Fab Fragment | FC, ADCC, CDC, FuncS | Humanized (mouse/human) Fab |
| HPAB-AP587-YC-F(E) | Human Anti-CD70 Recombinant Antibody (clone h1F6-HELA); Fab Fragment | FC, ADCC, CDC, FuncS | Humanized (mouse/human) Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H76 | Afuco™ Anti-CD70 ADCC Recombinant Antibody (Vorsetuzumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0468-WJ-S(P) | Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0468-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0469-WJ-S(P) | Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0469-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0470-WJ-S(P) | Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0470-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0471-WJ-S(P) | Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0471-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0472-WJ-S(P) | Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0472-WJ-S(P)) | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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