Recombinant Mouse Antibody (G99) is capable of binding to Coagulation factor VIII C2 domain, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 ELISA of C2-mAb interactions.
G99 IgG was incubated at various concentrations under the following conditions: ELISA wells coated with 3E6 Fab, blocked, and then coated with C2 (●); wells coated with 3E6 Fab and blocked (○); and wells blocked and then incubated with C2 domain only (■). Bound G99 IgG was detected using goat anti-mouse IgG-alkaline phosphatase.
Walter, J. D., Werther, R. A., Polozova, M. S., Pohlman, J., Healey, J. F., Meeks, S. L., ... & Spiegel, P. C. (2013). Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies. Journal of Biological Chemistry, 288(14), 9905-9914.
Figure 2 Bethesda assays for inhibition of fVIII activity in plasma.
Inhibition of fVIII activity by G99 whole IgG (○) and G99 Fab (●). 100% activity corresponds to the coagulation activity of pooled normal human plasma.
Walter, J. D., Werther, R. A., Polozova, M. S., Pohlman, J., Healey, J. F., Meeks, S. L., ... & Spiegel, P. C. (2013). Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies. Journal of Biological Chemistry, 288(14), 9905-9914.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-930-VHH | Recombinant Anti-Human F8 VHH Single Domain Antibody | ELISA, Neut, ICC, FC | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-259CL | Human Anti-F8 Recombinant Antibody (TAB-259CL) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-051 | Mouse Anti-F8 Recombinant Antibody (clone 3E6); scFv Fragment | ELISA, WB, FuncS | Mouse scFv |
PSBL-052 | Mouse Anti-F8 Recombinant Antibody (clone G99); scFv Fragment | ELISA, WB, FuncS | Mouse scFv |
HPAB-0096-YC-S(P) | Human Anti-F8 Recombinant Antibody (clone YK3.3.38); scFv Fragment | ELISA, FuncS | Human scFv |
FAMAB-0200JF-S(P) | Human Anti-F8 Recombinant Antibody (clone KM41); scFv Fragment | WB, ELISA, FuncS | Human scFv |
FAMAB-0201JF-S(P) | Human Anti-F8 Recombinant Antibody (clone KM38); scFv Fragment | WB, ELISA, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-016WM | Anti-Human F8 Recombinant Antibody (BOIIB2) | Inhib, ELISA | |
TAB-017WM | Anti-Human F8 Recombinant Antibody (4F50) | ELISA | |
TAB-016WM-S(P) | Anti-Human F8 Recombinant Antibody scFv Fragment (BOIIB2) | ELISA | |
TAB-016WM-F(E) | Anti-Human F8 Recombinant Antibody Fab Fragment (BOIIB2) | ELISA | |
TAB-017WM-F(E) | Anti-Human F8 Recombinant Antibody Fab Fragment (4F50) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-014LC | Recombinant Anti-Human F8 Antibody (Fab glycosylation) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-015LC | Recombinant Anti-Human F8 Antibody (Non-glycosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-058 | Recombinant Human Anti-F8 Antibody (BO2C11) | WB, ELISA, FuncS, Inhib, PK, IP, SPR | IgG |
PABX-058-S (P) | Recombinant Human Anti-F8 Antibody scFv Fragment (BO2C11) | WB, ELISA, FuncS | scFv |
PABX-058-F (E) | Recombinant Human Anti-F8 Antibody Fab Fragment (BO2C11) | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-765CQ | Mouse Anti-F8 Recombinant Antibody (clone CBL215) | ELISA, WB, Neut | Mouse IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1229 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone DS1229AB) | ELISA | Rabbit IgG |
MOR-4166 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI243DS) | ELISA | Rabbit IgG |
MOR-4167 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI244DS) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-0611LC | Human Anti-F8 Recombinant Antibody (clone BO2C11) | ELISA | Human IgG4 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0096-YC | Human Anti-F8 Recombinant Antibody (clone YK3.3.38) | ELISA, FuncS | Human IgG |
HPAB-1977-FY | Human Anti-F8 Recombinant Antibody (clone 92-137) | Inhib | Human IgG |
HPAB-1978-FY | Human Anti-F8 Recombinant Antibody (clone 92-102) | Inhib | Human IgG |
HPAB-1979-FY | Human Anti-F8 Recombinant Antibody (clone WR8) | IP | Human IgG4 |
HPAB-1980-FY | Human Anti-F8 Recombinant Antibody (clone WR11) | IP | Human IgG4 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0178CQ-F(E) | Mouse Anti-F8 Recombinant Antibody; Fab Fragment (HPAB-0178CQ-F(E)) | ELISA, DB, Inhib | Mouse Fab |
HPAB-0793-FY-S(P) | Mouse Anti-F8 Recombinant Antibody (clone 4F143); Fab Fragment | Activ | Mouse Fab |
HPAB-0794-FY-S(P) | Mouse Anti-F8 Recombinant Antibody (clone 4F50); Fab Fragment | Activ | Mouse Fab |
FAMAB-0037JF-F(E) | Human Anti-F8 Recombinant Antibody (clone MH8); Fab Fragment | IP, ELISA, FuncS | Human Fab |
FAMAB-0038JF-F(E) | Human Anti-F8 Recombinant Antibody (clone DH10); Fab Fragment | IP, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YF075 | DRB1*11:01/Factor VIII Factor VIII (ENIQRFLPNPAGVQLEDPEF) MHC Monomer | MHC Multimer |
There are currently no Customer reviews or questions for PABL-052. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.