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Anti-DDR1 scFv (20M102) (TAB-182MZ-S(P))

This antibody that binds to the stalk domain in the amino acid sequence of human DDR1 has a potent antitumor activity. It is also found that the antibody has one or more activities selected from the group consisting of: (i) an activity to suppress cell proliferation, (ii) an activity to inhibit cell migration, (iii) an activity to inhibit phosphorylation of DDR1 in cells, (iv) an activity to be taken up into cells, (v) an activity to decrease the expression level of DDR1 in cells, and (vi) an activity to decrease the expression level of TGF-β in cells.      

Specifications
Immunogen
A recombinant polypeptide fragment of the extracellular domain of human DDR1
Host
Mouse
Specificity
Human
Clone
20M102
Applications
Flow Cytometry
Related Disease
Lung carcinoma
Target
Alternative Names
DDR1; discoidin domain receptor tyrosine kinase 1; CAK; DDR; NEP; HGK2; PTK3; RTK6
Entrez Gene ID
780
UniProt ID
Q08345

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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