Anti-DENV1 E Recombinant Antibody (8F6) (CAT#: MRO-1090LC)

This product is a recombinant mouse anti-Dengue virus-1 monoclonal antibody derived from the hybridoma technology. The IgG2a isotype antibody 8F6 binds to the envelope protein of DENV type 1, with cross-reactivity against DENV type 3. With high affinity this product can be potentially used in the diagnosis research of of Dengue virus-1 infection.


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Specifications

  • Immunogen
  • A DNA vaccine expressing premembrane and E proteins of DENV-1
  • Host Species
  • Mouse
  • Type
  • Mouse Antibody
  • Specificity
  • Dengue virus-1
  • Clone
  • 8F6
  • Applications
  • ELISA, ADE
  • Related Disease
  • Dengue virus-1 infection

Applications

  • Application Notes
  • In the plaque reduction neutralization tests (PRNTs), the PRNT50 value of this product was 3.7. In the antibody-dependent enhancement (ADE) assay, the infection rate of U937 cells with this antibody in the absence of complement was 42%. It is positively reacted with DENV-1 and DENV-3 in ELISA assay.

Target

  • Alternative Names
  • Dengue virus-1; DENV1; Dengue virus-1 envelope protein E; DENV1 E
  • Long Name
  • Dengue virus-1 envelope protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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