Anti-DENV4 E Recombinant Antibody (MRO-1129LC) (CAT#: MRO-1129LC)

This product is a recombinant chimpanzee anti-Dengue virus monoclonal antibody specifically binding to the E protein. This full-length antibody selectively bind and neutralize dengue virus type 1, 2 with lower titer and dengue virus type 3 and 4 with higher titer in the PRNT50 assay. Produced in mammalian cells this antibody product was affinity-purified and could be biotinylated for the immunoassays and treatment studies about Dengue virus infection.


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ELISA

Figure 1 Analysis of Fab binding to DENV-1 or DENV-2.

Figure 1 Analysis of Fab binding to DENV-1 or DENV-2.

Fabs 1A5, 1B2, and 1A10 were affinity purified, biotinylated, and used for analysis of binding activity to DENV-1 or DENV-2 by competition ELISA in the presence of competing, unlabeled Fabs.

Chimpanzee Fab Fragments and a Derived Humanized Immunoglobulin G1 Antibody That Efficiently Cross-Neutralize Dengue Type 1 and Type 2 Viruses


Specifications

  • Host Species
  • Chimpanzee
  • Derivation
  • Phage display library
  • Type
  • Chimpanzee antibody
  • Specificity
  • Dengue virus-4
  • Clone
  • 1B2
  • Applications
  • ELISA
  • Related Disease
  • Dengue virus-4 infection

Applications

  • Application Notes
  • The DENV4 E antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Dengue virus-4; DENV4; Dengue virus-4 envelope protein E; DENV4 E
  • Long Name
  • Dengue virus-4 envelope protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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