Anti-DNA Antibody-Cytokine Fusion Protein, IgG (TNT)-IL2 (CAT#: ACFP-SH062)
This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-DNA IgG to IL2. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the DNA as well as the biological activity of IL2. The IL2 can specifically reach tumor parts, and can be used for reversing the local immunosuppression state of tumors and activating part bodies and integral antitumor immunity. This immunocytokine was designed for treating melanoma or lung cancer or other solid tumors.
Specific Inquiry
Specifications
- Target
- DNA
- Molecule Class
- L Kappa; IgG1-IL2
- Species Reactivity
- Human
- Expression Host
- CHO
- Clone
- TNT
- Related Disease
- Melanoma or lung cancer or other solid tumors
- Cytokine 1
- IL2
- Cytokines 1 Description
- Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes.
- Cytokine 1 Species
- Human
- Applications
- This product can be used therapeutically to deliver biologically active ligands to a desired tissue.
Target
- Alternative Names
- Deoxyribonucleic acid; ss DNA
Downloads
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Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-048 | Recombinant Mouse Anti-DNA Antibody | WB, ELISA, FuncS | IgG |
| PABX-048-F (E) | Recombinant Mouse Anti-DNA Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-048-S (P) | Recombinant Mouse Anti-DNA Antibody scFv Fragment | WB, ELISA, FuncS | scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0075CQ | Mouse Anti-DNA Recombinant Antibody (clone 16-13) | ELISA | Mouse IgG2a |
| FAMAB-0076CQ | Mouse Anti-DNA Recombinant Antibody (clone 1A11) | ELISA | Mouse IgG2b |
| FAMAB-0077CQ | Mouse Anti-DNA Recombinant Antibody (clone 1E81) | ELISA | Mouse IgG2a |
| FAMAB-0078CQ | Mouse Anti-DNA Recombinant Antibody (clone 2F2) | ELISA | Mouse IgG2b |
| FAMAB-0079CQ | Mouse Anti-DNA Recombinant Antibody (clone 3E12) | ELISA | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0085CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone BM24-11); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0086CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone BM24-28); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0087CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone BM9-7); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0088CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone BW9-15); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0089CQ-F(E) | Mouse Anti-DNA Recombinant Antibody (clone BW9-4); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-515 | Human Anti-DNA Recombinant Antibody (clone 71F12); scFv Fragment | ELISA, IF | Human scFv |
| FAMAB-0066WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone B4E7); scFv Fragment | WB | Human scFv |
| FAMAB-0067WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone D2C10); scFv Fragment | WB | Human scFv |
| FAMAB-0068WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone C6B2); scFv Fragment | WB | Human scFv |
| FAMAB-0066JF-S(P) | Mouse Anti-DNA Recombinant Antibody (clone 4B2); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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