This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-EDB scFv to IL12. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the EDB as well as the biological activity of IL12. The fusion protein displays an excellent tumor targeting performance in vivo. Considering the fact that the tumor targeting ability of scFv (L19) in patients with cancer has been demonstrated using scintigraphic methods, and that scFv (L19)-based antibody-cytokine fusion are currently entering clinical trials. This immunocytokine was designed for treating Advanced solid tumors, Advanced pancreatic cancer, Metastatic melanoma.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-001CQ | Anti-Human FN1 Recombinant Antibody (MOR03255) | ELISA, Block, IHC | Human antibody |
TAB-002CQ | Anti-Human FN1 Recombinant Antibody (ME-4C) | ELISA, IHC | Human antibody |
TAB-003CQ | Anti-Human FN1 Recombinant Antibody (1C5) | ELISA, WB | Human antibody |
TAB-004CQ | Human Anti-FN1 Recombinant Antibody (TAB-004CQ) | ELISA, IHC, WB | Human IgG |
TAB-001CQ-S(P) | Anti-Human FN1 Recombinant Antibody scFv Fragment (MOR03255) | ELISA, BL, IHC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-852CQ | Mouse Anti-FN1 Recombinant Antibody (clone HFN7.1) | ELISA, WB, IP, Block | Mouse IgG1 |
NEUT-853CQ | Mouse Anti-FN1 Recombinant Antibody (clone IST-9) | WB, RIA, ELISA, IHC-Fr, ICC, IF, Block, IHC-P | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1326 | Hi-Affi™ Rabbit Anti-FN1 Recombinant Antibody (clone DS1326AB) | IHC-Fr, IHC-P, IHC-P, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0193-CN-S(P) | Mouse Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-0193-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
HPAB-0194-CN-S(P) | Mouse Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-0194-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
HPAB-0195-CN-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-0195-CN-S(P)) | ELISA, FC, IHC | Human scFv |
HPAB-0196-CN-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-0196-CN-S(P)) | ELISA, FC, IHC | Human scFv |
FAMAB-0105-YC-S(P) | Human Anti-FN1 Recombinant Antibody (clone ME4C); scFv Fragment | ELISA, IHC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0193-CN-F(E) | Mouse Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0193-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
HPAB-0194-CN-F(E) | Mouse Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0194-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
HPAB-0195-CN-F(E) | Human Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0195-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
HPAB-0196-CN-F(E) | Human Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0196-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
FAMAB-0105-YC-F(E) | Human Anti-FN1 Recombinant Antibody (clone ME4C); Fab Fragment | ELISA, IHC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0105YC | Human Anti-FN1 Recombinant Antibody (clone ME4C) | ELISA, IHC | Human IgG |
ZG-0815F | Mouse Anti-FN1 Recombinant Antibody (clone EP5) | IHC | Mouse IgG1 |
ZG-0087U | Rabbit Anti-FN1 Recombinant Antibody (clone 1E1) | ELISA, IHC | Rabbit IgG |
VS3-QX434 | Mouse Anti-FN1 Recombinant Antibody (clone 2F4) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
VS3-XY717 | Mouse Anti-FN1 Recombinant Antibody (clone 3G4) | WB, IP, IF, IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NBD-0040-YJ-VHH | Camelid Anti-FN1 Recombinant Single Domain Antibody (NJB2) | ELISA, In vivo imaging | Camelid VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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