Afuco™ Anti-Human EPHA3 ADCC Recombinant Antibody (KB004), ADCC Enhanced (CAT#: AFC-225CL)

Anti-EPHA3 ADCC Enhanced Antibody (KB004) is an ADCC enhanced antibody produced by our Afuco™ platform. KB004 is a first-in-class, monoclonal antibody targeting the EphA3 receptor tyrosine kinase. KB004 has the potential to attack tumors at their source by killing tumor stem cells, the tumor stromal cells that protect them, and the vasculature that feeds them. This unique activity provides the potential to generate durable responses by targeting the source of tumor cells. KB004 has been shown to be expressed in many tumor types, including hematologic malignancies and solid tumors.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Chimeric (human/mouse)
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Hematologic malignancies; Solid Tumors

Product Property

  • Purity
  • >95% as determined by analysis by RP-HPLC
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • EPHA3; EPH receptor A3; EK4; ETK; HEK; ETK1; HEK4; TYRO4; ephrin type-A receptor 3; EPH-like kinase 4; human embryo kinase 1; eph-like tyrosine kinase 1; TYRO4 protein tyrosine kinase; tyrosine-protein kinase receptor ETK1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "EPHA3"

Human Antibody

CAT Product Name Application Type
TAB-237CL Anti-Human EPHA3 Recombinant Antibody (KB004) IHC, WB, IF, FC Antibody

Fc Glycosylation

CAT Product Name Application Type
Gly-101LC Recombinant Anti-Human EPHA3 Antibody (Fc glycosylation/Low fucosylated) ELISA Human antibody

Low- or Non-fucosylated Oligosaccharide

CAT Product Name Application Type
Gly-101LC-1 Recombinant Anti-Human EPHA3 Antibody (Fc glycosylation/Low fucosylated) ELISA Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1165 Hi-Affi™ Rabbit Anti-EPHA3 Recombinant Antibody (clone DS1165AB) WB Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
TAB-024ML Anti-Human EPHA3 Recombinant Antibody (Fibatuzumab) ELISA, IHC, FC, IP, IF, FuncS IgG1, κ
TAB-430CQ Anti-Human EPHA3 Recombinant Antibody (Ifabotuzumab) ELISA, IHC, FC, IP, IF, FuncS IgG1, κ

scFv Fragment Antibody

Fab Fragment Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-024ML Afuco™ Anti-EPHA3 ADCC Recombinant Antibody (Fibatuzumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-430CQ Afuco™ Anti-EPHA3 ADCC Recombinant Antibody (Ifabotuzumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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