This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-EpCAM IgG to IL12. It was expressed in CHO and purified with affinity chromatography. The Immunocytokines retains the ability to bind the EpCAM as well as the biological activity of IL12. Fusion proteins composed of the human p35 and p40 subunits had IL12 bioactivities that were nearly as potent on human immune cells as the rIL12 standard, but were inactive on mouse cells. This Immunocytokines was designed for treating solid tumor.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-701 | Anti-Human EpCAM/17-1A Recombinant Antibody (Edrecolomab) | ELISA, IP, FC, FuncS, IF, Neut | IgG2a - kappa |
TAB-363MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-363MZ-S(P)) | Confocal, ELISA | Mouse scFv |
TAB-364MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-364MZ-S(P)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse scFv |
TAB-365MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-365MZ-S(P)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse scFv |
TAB-366MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-366MZ-S(P)) | ELISA, WB, IHC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L013O | anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-235CL | Human Anti-Human EPCAM Recombinant Antibody (3622W94) | Cyt, FC | Antibody |
TAB-374MZ | Anti-Human EPCAM Recombinant Antibody (h12H8B) | FC, ELISA | Humanized antibody |
TAB-375MZ | Anti-Human EPCAM Recombinant Antibody (h12H8C) | FuncS, Inhib | Humanized antibody |
TAB-375MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h12H8C) | FC, ELISA | Humanized antibody |
TAB-376MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h2D11B) | FC, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-356MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (3-171) | FC, ELISA | Human antibody |
TAB-357MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (7-F17) | FC, ELISA | Human antibody |
TAB-358MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (12-C15) | FC, ELISA | Human antibody |
TAB-359MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (16-G5) | FC, ELISA | Human antibody |
TAB-360MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (17-C20) | FC, ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1163 | Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) | IHC-P, WB, ICC, ICC, IF | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-074LC | Human Anti-EPCAM Recombinant Antibody (clone ING-1) | ELISA, FuncS | Humanized IgG1, κ |
FAMAB-0095YC | Mouse Anti-EPCAM Recombinant Antibody (clone MOC31) | ELISA | Mouse IgG1, κ |
FAMAB-0129CQ | Human Anti-EPCAM Recombinant Antibody (clone 17-1A) | ELISA, IHC, FC | Chimeric (mouse/human) IgG |
FAMAB-0130CQ | Human Anti-EPCAM Recombinant Antibody (clone 323/A3) | ELISA, IHC, FC | Chimeric (mouse/human) IgG |
FAMAB-0131CQ | Mouse Anti-EPCAM Recombinant Antibody (clone MOC-161) | ELISA, IHC, FC | Mouse IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-106 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Adecatumumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
AFC-TAB-213 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Tucotuzumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
AFC-TAB-701 | Afuco™ Anti-EpCAM ADCC Recombinant Antibody (Edrecolomab), ADCC Enhanced | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2218LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2218LY-F(E)) | ELISA | Human Fab |
HPAB-2219LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2219LY-F(E)) | ELISA | Human Fab |
HPAB-2220LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2220LY-F(E)) | ELISA | Human Fab |
HPAB-2221LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2221LY-F(E)) | ELISA | Human Fab |
HPAB-2222LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2222LY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0031 | APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM | |
MHC-CN0032 | PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP343-YC-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-AP343-YC-S(P)) | ELISA, WB | Humanized scFv |
HPAB-S0025-YC-S(P) | Mouse Anti-EPCAM Recombinant Antibody (clone M79); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-S0026-YC-S(P) | Human Anti-EPCAM Recombinant Antibody (clone H79); scFv Fragment | ELISA, FC, Cyt | Human scFv |
HPAB-2050-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone K53); scFv Fragment | FC | Human scFv |
HPAB-2051-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone 02-237); scFv Fragment | FC | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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