This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-EpCAM IgG to IL2. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the EpCAM as well as the biological activity of IL2. This bi-antibody-cytokine fusion protein showed effective antigen binding and cytokine activity. KS-(IL12/IL2) exhibits significant antitumor activity, similar to that observed when the combination of KS-(IL2) and KS-(IL12) was used. This immunocytokine was designed for treating solid tumor.
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CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L013O | anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0531CL-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (HE2) | ELISA, Inhib | |
TAB-363MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-363MZ) | ELISA, FuncS | Mouse IgG1, κ |
TAB-364MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-364MZ) | FC | Mouse IgG1 |
TAB-365MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-365MZ) | FC | Mouse IgG1 |
TAB-366MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-366MZ) | ELISA, FC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-356MZ | Anti-Human EPCAM Recombinant Antibody (3-171) | Cyt, ELISA, FC, WB | Human antibody |
TAB-357MZ | Anti-Human EPCAM Recombinant Antibody (7-F17) | ELISA | Human antibody |
TAB-358MZ | Anti-Human EPCAM Recombinant Antibody (12-C15) | ELISA | Human antibody |
TAB-359MZ | Anti-Human EPCAM Recombinant Antibody (16-G5) | ELISA | Human antibody |
TAB-360MZ | Anti-Human EPCAM Recombinant Antibody (17-C20) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-374MZ | Anti-Human EPCAM Recombinant Antibody (h12H8B) | FC, ELISA | Humanized antibody |
TAB-375MZ | Anti-Human EPCAM Recombinant Antibody (h12H8C) | FuncS, Inhib | Humanized antibody |
TAB-376MZ | Anti-Human EPCAM Recombinant Antibody (h2D11B) | Cyt, Inhib | Humanized antibody |
TAB-362MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (3622W94) | Confocal, ELISA | Humanized antibody |
TAB-374MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (h12H8B) | FC, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1163 | Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) | IHC-P, WB, ICC, ICC, IF | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0095YC | Mouse Anti-EPCAM Recombinant Antibody (clone MOC31) | ELISA | Mouse IgG1, κ |
HPAB-0163CQ | Human Anti-EPCAM Recombinant Antibody (clone HuMAB UBS-54) | ELISA, FC, FuncS | Human IgG1 |
MRO-0537-CN | Rabbit Anti-EPCAM Recombinant Antibody (clone CBACN-213) | WB, IHC | Rabbit IgG |
MRO-0538-CN | Mouse Anti-EPCAM Recombinant Antibody (clone 3-E1-E2) | WB, IF, IHC, FC | Mouse IgM |
MRO-1842-CN | Rabbit Anti-EPCAM Polyclonal Antibody (MRO-1842-CN) | WB, IF, IHC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-106 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Adecatumumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
AFC-TAB-213 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Tucotuzumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
AFC-TAB-701 | Afuco™ Anti-EpCAM ADCC Recombinant Antibody (Edrecolomab), ADCC Enhanced | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2216LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2216LY-F(E)) | ELISA | Human Fab |
HPAB-2217LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2217LY-F(E)) | ELISA | Human Fab |
HPAB-2218LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2218LY-F(E)) | ELISA | Human Fab |
HPAB-2219LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2219LY-F(E)) | ELISA | Human Fab |
HPAB-2220LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2220LY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2233LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2233LY-S(P)) | ELISA | Human scFv |
HPAB-2234LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2234LY-S(P)) | ELISA | Human scFv |
HPAB-2235LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2235LY-S(P)) | ELISA | Human scFv |
HPAB-2236LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2236LY-S(P)) | ELISA | Human scFv |
HPAB-2051-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone 02-237); scFv Fragment | FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0031 | APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM | |
MHC-CN0032 | PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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