Human Anti-F3 Recombinant Antibody (clone 10H10) (CAT#: PABL-471)
Recombinant Human Antibody (10H10) is capable of binding to F3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-F3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-F3 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Inhib
Figure 1 Cell spreading of HaCaT keratinocytes on anti-TF involves several β1 integrins.
Inhibitory mAB 10H10 was added at 25 μg/ml before plating.
Dorfleutner, A., Hintermann, E., Tarui, T., Takada, Y., & Ruf, W. (2004). Cross-talk of integrin α3β1 and tissue factor in cell migration. Molecular biology of the cell, 15(10), 4416-4425.
Specifications
- Immunogen
- Human coagulation factor III (thromboplastin, tissue factor)
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human F3
- Species Reactivity
- Human
- Clone
- 10H10
- Applications
- WB, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Inhibition.
Target
- Alternative Names
- F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor
- Gene ID
- 2152
- UniProt ID
- P13726
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone 10H10"
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-258CL | Human Anti-F3 Recombinant Antibody (TAB-258CL) | ELISA | Human IgG |
| TAB-276CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-276CQ-S(P)) | ELISA, FC | Humanized scFv |
| TAB-278CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-278CQ-S(P)) | ELISA, FC | Humanized scFv |
| TAB-276CQ-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (TAB-276CQ-F(E)) | ELISA, FC | Humanized Fab |
| TAB-278CQ-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (TAB-278CQ-F(E)) | ELISA, FC | Humanized Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-043 | Mouse Anti-F3 Recombinant Antibody (clone 5G9); Fab Fragment | Block | Mouse Fab |
| PFBW-043 | Human Anti-F3 Recombinant Antibody (clone D3H44); Fab Fragment | WB, IHC, IF, FuncS | Humanized Fab |
| PFBL-468 | Human Anti-F3 Recombinant Antibody (clone 10H10); Fab Fragment | WB, IF, FuncS | Human Fab |
| PFBC-450 | Mouse Anti-F3 Recombinant Antibody (clone 10H10); Fab Fragment | ELISA, FuncS | Mouse Fab |
| HPAB-1000WJ-F(E) | Human Anti-F3 Recombinant Antibody (clone JT C5); Fab Fragment | ELISA, Inhib | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-468 | Human Anti-F3 Recombinant Antibody (clone 10H10); scFv Fragment | WB, IF, FuncS | Human scFv |
| HPAB-0113-YC-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-0113-YC-S(P)) | ELISA, FC, Neut | Human scFv |
| HPAB-0114-YC-S(P) | Mouse Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-0114-YC-S(P)) | ELISA | Mouse scFv |
| PSBC-450 | Mouse Anti-F3 Recombinant Antibody (clone 10H10); scFv Fragment | ELISA, FuncS | Mouse scFv |
| HPAB-1000WJ-S(P) | Human Anti-F3 Recombinant Antibody (clone JT C5); scFv Fragment | ELISA, Inhib | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-277CQ-S(P) | Mouse Anti-F3 Recombinant Antibody; scFv Fragment (TAB-277CQ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-277CQ-F(E) | Mouse Anti-F3 Recombinant Antibody; Fab Fragment (TAB-277CQ-F(E)) | ELISA, FC | Mouse Fab |
| PABX-179 | Recombinant Mouse Anti-TF Antibody (D3) | WB, ELISA, IF, FuncS | IgG |
| PABX-177-S (P) | Recombinant Human Anti-TF Antibody scFv Fragment (D3h44) | WB, ELISA, Neut, FuncS | scFv |
| PABX-179-S (P) | Recombinant Mouse Anti-TF Antibody scFv Fragment (D3) | WB, ELISA, IF, FuncS | scFv |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-178LC | Recombinant Anti-Human F3 Antibody (Non-glycosylated) | ELISA | Human antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0373MZ | Recombinant Mouse Anti-Human Tissue Factor Antibody (clone BIUG-5265) | RIA, WB, ELISA | Mouse antibody |
| MOB-2336MZ | Recombinant Mouse Anti-Human F3 Antibody (clone 3L2) | ELISA, ICC/IF, IHC-Fr, IHC-P, IHC-P, WB | Mouse antibody |
| PABC-450 | Mouse Anti-F3 Recombinant Antibody (clone 10H10) | ELISA, FuncS | Mouse IgG1, κ |
| FN-224CQ | Mouse Anti-F3 Recombinant Antibody (clone HTF-1) | FC, FuncS, ICC, IF, WB | Mouse IgG1, κ |
| HPAB-J0088-YC | Human Anti-F3 Recombinant Antibody (HPAB-J0088-YC) | ELISA, FC, IHC, FuncS | Human IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1226 | Hi-Affi™ Rabbit Anti-F3 Recombinant Antibody (clone DS1226AB) | WB, IHC-P, ICC, IF | Rabbit IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-473CQ | Anti-Human F3 Recombinant Antibody (Tisotumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0573CQ | Mouse Anti-F3 Recombinant Antibody (clone hATR-5) | ELISA, Inhib | Mouse IgG4 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-473CQ | Afuco™ Anti-F3 ADCC Recombinant Antibody (Tisotumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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