Anti-Human FGFR1 Recombinant Antibody (FR1-H7) (CAT#: TAB-052WM)
Antibody FR1-H7 binds FGFR-1(IIIb) and -1(IIIc) with strong affinities, but does not recognize any of the other FGFRs. Results from kinetic analysis indicated the antibody binds to FGFR-1b and -1c equally well. The KDs of the interactions were determined to be approximately 50 μM for both receptors. This product can be potentially used for antagonizing EGFR-1 or EGFR-4 as a treatment for obesity, diabetes, or a condition related thereto, and methods of reducing food intake.
Specific Inquiry
ELISA
Figure 1 Binding of FR1-H7 antibody to FGFRs as determined using the ELISA binding assay.
Each data point is an average of duplicates and error bars are standard devia tions.
Specifications
- Host Species
- Human
- Derivation
- Phage-displayed human Fab library
- Type
- Human Antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- FR1-H7
- Applications
- ELISA, Neut
- Related Disease
- Obesity, diabetes
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Neutralization. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; FGFR1/PLAG1 fusion; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1
- Gene ID
- 2260
- UniProt ID
- P11362
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone FR1-H7"
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-283CL | Human Anti-FGFR1 Recombinant Antibody (TAB-283CL) | WB, IHC | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-053WM | Mouse Anti-FGFR1 Recombinant Antibody (TAB-053WM) | WB, FC | Mouse IgG |
| TAB-053WM-S(P) | Mouse Anti-FGFR1 Recombinant Antibody; scFv Fragment (TAB-053WM-S(P)) | WB | Mouse scFv |
| TAB-053WM-F(E) | Mouse Anti-FGFR1 Recombinant Antibody; Fab Fragment (TAB-053WM-F(E)) | WB | Mouse Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-054WM | Human Anti-FGFR1 Recombinant Antibody (TAB-054WM) | ELISA | Human IgG |
| TAB-052WM-S(P) | Anti-Human FGFR1 Recombinant Antibody scFv Fragment (FR1-H7) | ELISA, BL, Neut | Human Antibody |
| TAB-054WM-S(P) | Human Anti-FGFR1 Recombinant Antibody; scFv Fragment (TAB-054WM-S(P)) | ELISA | Human scFv |
| TAB-052WM-F(E) | Anti-Human FGFR1 Recombinant Antibody Fab Fragment (FR1-H7) | ELISA, BL, Neut | Human Antibody |
| TAB-054WM-F(E) | Human Anti-FGFR1 Recombinant Antibody; Fab Fragment (TAB-054WM-F(E)) | ELISA | Human Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-825CQ | Mouse Anti-FGFR1 Recombinant Antibody (clone CBL537) | WB, Neut | Mouse IgG1 |
| NEUT-826CQ | Mouse Anti-FGFR1 Recombinant Antibody (clone MM0277-6F10) | WB, Neut | Mouse IgG1 |
| NEUT-827CQ | Mouse Anti-FGFR1 Recombinant Antibody (clone CBL059) | Neut, WB | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1296 | Hi-Affi™ Rabbit Anti-FGFR1 Recombinant Antibody (clone DS1296AB) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0118-FY | Human Anti-FGFR1 Recombinant Antibody (HPAB-0118-FY) | ELISA | Human IgG1 |
| HPAB-N0346-YC | Human Anti-FGFR1 Recombinant Antibody (clone SEEDbody A08) | ELISA, FuncS | Human IgG1 |
| HPAB-0489LY | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-C7) | ELISA | Human IgG |
| HPAB-0490LY | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-E1) | ELISA | Human IgG |
| VS3-QX429 | Mouse Anti-FGFR1 Recombinant Antibody (clone 1440CT772.50.23) | WB, ICC, IHC | Mouse IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0118-FY-S(P) | Human Anti-FGFR1 Recombinant Antibody; scFv Fragment (HPAB-0118-FY-S(P)) | ELISA | Human scFv |
| HPAB-N0346-YC-S(P) | Human Anti-FGFR1 Recombinant Antibody (clone SEEDbody A08); scFv Fragment | ELISA, FuncS | Human scFv |
| HPAB-0485LY-S(P) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A7/C6/D9); scFv Fragment | ELISA | Human scFv |
| HPAB-0486LY-S(P) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A9/H10); scFv Fragment | ELISA | Human scFv |
| HPAB-0701-FY-F(E) | Mouse Anti-FGFR1 Recombinant Antibody (clone Ab21); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0118-FY-F(E) | Human Anti-FGFR1 Recombinant Antibody; Fab Fragment (HPAB-0118-FY-F(E)) | ELISA | Human Fab |
| HPAB-N0346-YC-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone SEEDbody A08); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-0485LY-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A7/C6/D9); Fab Fragment | ELISA | Human Fab |
| HPAB-0486LY-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A9/H10); Fab Fragment | ELISA | Human Fab |
| HPAB-3044LY-F(E) | Mouse Anti-FGFR1 Recombinant Antibody; Fab Fragment (HPAB-3044LY-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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