Atto-MuMab-01 is a human IgG1 isotype and can elicit strong immune responses of antibody-dependent cellular cytotoxicity (ADCC) and complement-mediated cell lysis. And Atto-MuMab-01 can be a potentially therapeutic agent in prostate cancer.
Figure 1 depicts exemplary Atto-HuMab-01 properties.
Atto-HuMab-01 binding activity to soluble receptor FGFR2-IIIc Loop-III domain (mFc-128aa); negative control=Human IgG.
Figure 2 depicts exemplary Atto-HuMab-01 affinity determination.
Atto-HuMab-01 binds to a soluble receptor with calculated affinity constant 0.04 nM (0.01 nM-0.1 nM).
Figure 3 depicts exemplary Atto-HuMab-01 affinity determination.
Atto-HuMab-01 binds to cell receptor FGFR2-IIIc on stable CHO-IIIc cell with a calculated affinity constant 0.7 nM.
Figure 4 depicts exemplary Atto-HuMab-01 affinity determination.
Atto-HuMab-01 binds to with varying affinity to a subset of FGF receptors. Atto-HuMab-01 (biotinylated) binds to FGFR2-IIIc with similar affinity as previously determined (affinity ˜0.2 nM). Atto-HuMab-01 binds to FGFR3-IIIc, FGFR4 with lower affinity.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B026(A) | Recombinant Anti-human FGFR2 Intrabody [(D-Arg)9] | IF, FC, FuncS | scFv-(D-Arg)9 |
IAB-B026(G) | Recombinant Anti-human FGFR2 Intrabody [+36 GFP] | WB, ICC, FuncS | scFv-(+36GFP) |
IAB-B026(T) | Recombinant Anti-human FGFR2 Intrabody [Tat] | ICC, Neut, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-284CL | Anti-Human FGFR2 Recombinant Antibody (BAY 1179470) | IF, WB | Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-055WM | Anti-Human FGFR2 Recombinant Antibody (GP369/4B9) | FC | |
TAB-055WM-S(P) | Anti-Human FGFR2 Recombinant Antibody scFv Fragment (GP369/4B9) | ELISA, FC | |
TAB-056WM-S(P) | Mouse Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-056WM-S(P)) | ELISA, FC, Block | Mouse scFv |
TAB-058WM-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-058WM-S(P)) | ELISA, FC, Neut, Inhib | Rat scFv |
TAB-059WM-S(P) | Anti-Human FGFR2 Recombinant Antibody scFv Fragment (Atto-MuMab-01) | ELISA, WB, FC |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-057WM | Human Anti-FGFR2 Recombinant Antibody (TAB-057WM) | ELISA, FC, Block | Human IgG1 |
TAB-057WM-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-057WM-S(P)) | ELISA, FC, Block | Human scFv |
TAB-057WM-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-057WM-F(E)) | ELISA, FC, Block | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-060WM | Anti-Human FGFR2 Recombinant Antibody (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
TAB-061WM | Human Anti-FGFR2 Recombinant Antibody (TAB-061WM) | Neut, WB, ELISA | Human IgG |
TAB-060WM-S(P) | Anti-Human FGFR2 Recombinant Antibody scFv Fragment (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
TAB-061WM-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-061WM-S(P)) | Neut, WB, ELISA | Human scFv |
TAB-061WM-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-061WM-F(E)) | Neut, WB, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-828CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL511) | WB, Neut | Mouse IgG1 |
NEUT-829CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL512) | WB, FC, CyTOF®, Neut | Mouse IgG1 |
NEUT-830CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL513) | FC, IHC, CyTOF®, Neut | Mouse IgG1 |
NEUT-831CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone 6L19) | IHC, Neut, WB | Mouse IgG1 |
NEUT-832CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL060) | Neut, WB, IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1298 | Hi-Affi™ Rabbit Anti-FGFR2 Recombinant Antibody (clone DS1298AB) | WB, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0144-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone Hu4B9-65); Fab Fragment | FuncS | Humanized Fab |
HPAB-0146-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-0146-YC-F(E)) | ELISA, FC, Neut | Human Fab |
HPAB-0147-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-0147-YC-F(E)) | ELISA, FC, Neut | Humanized Fab |
HPAB-0098-WJ-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone 15492.77); Fab Fragment | ELISA | Human Fab |
HPAB-0135-WJ-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-0135-WJ-F(E)) | ELISA, FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-027CN | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01) | ELISA, WB, FC | Human IgG1 |
NS-027CN-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); Fab Fragment | ELISA, WB, FC | Human Fab |
NS-027CN-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); scFv Fragment | ELISA, WB, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1861-CN | Rabbit Anti-FGFR2 Polyclonal Antibody (MRO-1861-CN) | WB, FC | Rabbit IgG |
MRO-1862-CN | Rabbit Anti-FGFR2 Polyclonal Antibody (MRO-1862-CN) | WB, IF, IHC, FC | Rabbit IgG |
HPAB-0791-FY | Mouse Anti-FGFR2 Recombinant Antibody (HPAB-0791-FY) | ELISA | Mouse IgG |
HPAB-0674-WJ | Human Anti-FGFR2 Recombinant Antibody (clone M047-D08) | ELISA, FC | Human IgG |
HPAB-0675-WJ | Human Anti-FGFR2 Recombinant Antibody (clone M017-B02) | ELISA, FC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0098-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone 15492.77); scFv Fragment | ELISA | Human scFv |
HPAB-0135-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-0135-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-AP348-YC-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-AP348-YC-S(P)) | ELISA, FC, Neut, ADCC, FuncS | Rat scFv |
HPAB-AP349-YC-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-AP349-YC-S(P)) | ELISA, FC, Neut, ADCC, FuncS | Rat scFv |
HPAB-AP350-YC-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-AP350-YC-S(P)) | ELISA, FC, Neut, ADCC, FuncS | Rat scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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