Anti-Human FGFR2 Recombinant Antibody scFv Fragment (Atto-MuMab-01) (CAT#: TAB-059WM-S(P))
Atto-MuMab-01 is a human IgG1 isotype and can elicit strong immune responses of antibody-dependent cellular cytotoxicity (ADCC) and complement-mediated cell lysis. And Atto-MuMab-01 can be a potentially therapeutic agent in prostate cancer.
Specific Inquiry
-1.png)
Figure 1 depicts exemplary Atto-HuMab-01 properties.
Atto-HuMab-01 binding activity to soluble receptor FGFR2-IIIc Loop-III domain (mFc-128aa); negative control=Human IgG.
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Figure 2 depicts exemplary Atto-HuMab-01 affinity determination.
Atto-HuMab-01 binds to a soluble receptor with calculated affinity constant 0.04 nM (0.01 nM-0.1 nM).
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Figure 3 depicts exemplary Atto-HuMab-01 affinity determination.
Atto-HuMab-01 binds to cell receptor FGFR2-IIIc on stable CHO-IIIc cell with a calculated affinity constant 0.7 nM.
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Figure 4 depicts exemplary Atto-HuMab-01 affinity determination.
Atto-HuMab-01 binds to with varying affinity to a subset of FGF receptors. Atto-HuMab-01 (biotinylated) binds to FGFR2-IIIc with similar affinity as previously determined (affinity ˜0.2 nM). Atto-HuMab-01 binds to FGFR3-IIIc, FGFR4 with lower affinity.
Specifications
- Immunogen
- FGFR2: isoform FGFR2-IIIc
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- Atto-MuMab-01
- Applications
- ELISA, WB, FC
- Related Disease
- Prostate Cancer
Target
- Alternative Names
- FGFR2; fibroblast growth factor receptor 2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14
- Gene ID
- 2263
- UniProt ID
- P21802
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B026(A) | Recombinant Anti-human FGFR2 Intrabody [(D-Arg)9] | IF, FC, FuncS | scFv-(D-Arg)9 |
| IAB-B026(G) | Recombinant Anti-human FGFR2 Intrabody [+36 GFP] | WB, ICC, FuncS | scFv-(+36GFP) |
| IAB-B026(T) | Recombinant Anti-human FGFR2 Intrabody [Tat] | ICC, Neut, FuncS | scFv-Tat |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-284CL | Anti-Human FGFR2 Recombinant Antibody (BAY 1179470) | IF, WB | Antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-057WM | Human Anti-FGFR2 Recombinant Antibody (TAB-057WM) | ELISA, FC, Block | Human IgG1 |
| TAB-057WM-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-057WM-S(P)) | ELISA, FC, Block | Human scFv |
| TAB-057WM-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-057WM-F(E)) | ELISA, FC, Block | Humanized Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-060WM | Anti-Human FGFR2 Recombinant Antibody (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
| TAB-060WM-S(P) | Anti-Human FGFR2 Recombinant Antibody scFv Fragment (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
| TAB-061WM-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-061WM-S(P)) | Neut, WB, ELISA | Human scFv |
| TAB-060WM-F(E) | Anti-Human FGFR2 Recombinant Antibody Fab Fragment (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
| TAB-061WM-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-061WM-F(E)) | Neut, WB, ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-055WM-S(P) | Anti-Human FGFR2 Recombinant Antibody scFv Fragment (GP369/4B9) | ELISA, FC | |
| TAB-055WM-F(E) | Anti-Human FGFR2 Recombinant Antibody Fab Fragment (GP369/4B9) | ELISA, FC | |
| TAB-056WM-F(E) | Mouse Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-056WM-F(E)) | ELISA, FC, Block | Mouse Fab |
| TAB-058WM-F(E) | Rat Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-058WM-F(E)) | ELISA, FC, Neut, Inhib | Rat Fab |
| TAB-059WM-F(E) | Anti-Human FGFR2 Recombinant Antibody Fab Fragment (Atto-MuMab-01) | ELISA, WB, FC |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-828CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL511) | WB, Neut | Mouse IgG1 |
| NEUT-829CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL512) | WB, FC, CyTOF®, Neut | Mouse IgG1 |
| NEUT-830CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL513) | FC, IHC, CyTOF®, Neut | Mouse IgG1 |
| NEUT-831CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone 6L19) | IHC, Neut, WB | Mouse IgG1 |
| NEUT-832CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL060) | Neut, WB, IHC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1298 | Hi-Affi™ Rabbit Anti-FGFR2 Recombinant Antibody (clone DS1298AB) | WB, IP | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-YC | Human Anti-FGFR2 Recombinant Antibody (clone Hu4B9-65) | FuncS | Humanized IgG1, κ |
| MRO-0579-CN | Rabbit Anti-FGFR2 Recombinant Antibody (clone JM10-60) | WB, IP | Rabbit IgG |
| MRO-0580-CN | Mouse Anti-FGFR2 Recombinant Antibody (clone 1-F1-E7) | WB, IF, FC | Mouse IgG1 |
| MRO-0581-CN | Mouse Anti-FGFR2 Recombinant Antibody (clone A5-E10-G7) | WB, IF, IHC | Mouse IgG1 |
| HPAB-0791-FY | Mouse Anti-FGFR2 Recombinant Antibody (HPAB-0791-FY) | ELISA | Mouse IgG |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-027CN | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01) | ELISA, WB, FC | Human IgG1 |
| NS-027CN-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); Fab Fragment | ELISA, WB, FC | Human Fab |
| NS-027CN-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); scFv Fragment | ELISA, WB, FC | Human scFv |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0020-FY-S(P) | Mouse Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-0020-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-0791-FY-F(E) | Mouse Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-0791-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-0098-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone 15492.77); scFv Fragment | ELISA | Human scFv |
| HPAB-0135-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-0135-WJ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0674-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M047-D08); scFv Fragment | ELISA, FC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0098-WJ-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone 15492.77); Fab Fragment | ELISA | Human Fab |
| HPAB-AP348-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-AP348-YC-F(E)) | ELISA, FC, Neut, ADCC, FuncS | Chimeric (rat/human) Fab |
| HPAB-AP349-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-AP349-YC-F(E)) | ELISA, FC, Neut, ADCC, FuncS | Chimeric (rat/human) Fab |
| HPAB-AP350-YC-F(E) | Rat Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-AP350-YC-F(E)) | ELISA, FC, Neut, ADCC, FuncS | Rat Fab |
| HPAB-AP351-YC-F(E) | Rat Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-AP351-YC-F(E)) | ELISA, FC, Neut, ADCC, FuncS | Rat Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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