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Afuco™ Anti-Human FGFR3 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-272CL)

Anti-FGFR3 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an anti-FGFR3 antibody used for the treatment or prevention of disease, such as cancer, tumor and cell proliferative disorder.


See more Engineered Antibody products for FGFR3
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  • Datasheet
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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67204/1419_D10_2_selected.jpg
Figure 2 IF staining of human cell line RT4
Figure 2 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67204/1382_D10_2_blue_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4231/11838_B_7_5.jpg
Figure 4 Testis
Figure 4 Testis
(Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4231/11838_A_6_6.jpg
Figure 5 Skin
Figure 5 Skin
(Cells in basal layer
Staining: High
Intensity: Strong
Quantity:>75%
Cells in spinous layer
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Langerhans cells
Staining: Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4231/11838_B_8_1.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, HaCaT, Hep G2, NTERA-2, RT4)
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, HaCaT, Hep G2, NTERA-2, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000068078-FGFR3
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, HaCaT, Hep G2, NTERA-2, RT4)
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, HaCaT, Hep G2, NTERA-2, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000068078-FGFR3

Specifications

  • Host Species
  • Humanized
  • Derivation
  • Humanized
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Cancer

Product Property

  • Purity
  • 90–95% (SDS-PAGE)
  • Storage
  • Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.

Target

  • Alternative Names
  • FGFR3; fibroblast growth factor receptor 3; ACH; CEK2; JTK4; CD333; HSFGFR3EX; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; fibroblast growth factor receptor 3 variant 4

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "FGFR3"

Recombinant Antibody

CAT Product Name Application Type
MOB-1249z Mouse Anti-FGFR3 Recombinant Antibody (clone 3F6) WB, ELISA, FC Mouse IgG2a
PABL-095 Human Anti-FGFR3 Recombinant Antibody (clone 2B.1.3) ELISA, WB, IF, FuncS Human IgG
PABL-474 Human Anti-FGFR3 Recombinant Antibody (clone R3Mab) ELISA Human IgG
HPAB-0150-WJ Human Anti-FGFR3 Recombinant Antibody (HPAB-0150-WJ) ELISA Human IgG1
VS3-FY549 Recombinant Rabbit Anti-FGFR3 Antibody (clone R06-6F4) WB, IHC-Fr, IHC-P, ICC, IF Rabbit IgG

Immunotoxin

CAT Product Name Application Type
AGTO-G028E Anti-FGFR3 immunotoxin (scFv)-PE Cytotoxicity assay, Function study
AGTO-G028G Anti-FGFR3 immunotoxin (scFv)-Gel Cytotoxicity assay, Function study
AGTO-L016E aFGF-PE immunotoxin Cytotoxicity assay, Functional assay
AGTO-L016G aFGF-Gel immunotoxin Cytotoxicity assay, Functional assay

scFv Fragment Antibody

CAT Product Name Application Type
PFBW-162 Human Anti-FGFR3 Recombinant Antibody (clone R3); Fab Fragment Neut, ELISA, FC Human Fab
PSBL-471 Human Anti-FGFR3 Recombinant Antibody (clone R3Mab); scFv Fragment ELISA Human scFv
HPAB-0157-YC-S(P) Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0157-YC-S(P)) ELISA, IP, WB Human scFv
HPAB-0158-YC-S(P) Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0158-YC-S(P)) ELISA, FC Mouse scFv
HPAB-0159-YC-S(P) Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1); scFv Fragment ELISA, FuncS Human scFv

Mouse Antibody

CAT Product Name Application Type
TAB-062WM Mouse Anti-FGFR3 Recombinant Antibody (TAB-062WM) ELISA, FC, Neut, WB Mouse IgG
TAB-063WM Mouse Anti-FGFR3 Recombinant Antibody (TAB-063WM) ELISA, FC, Neut, WB Mouse IgG
TAB-062WM-S(P) Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-062WM-S(P)) ELISA, FC, Neut, WB Mouse scFv
TAB-063WM-S(P) Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-063WM-S(P)) ELISA, FC, Neut, WB Mouse scFv
TAB-064WM-S(P) Anti-Human FGFR3 Recombinant Antibody scFv Fragment (15D8) Neut, ELISA

Neutralizing Antibody

CAT Product Name Application Type
NEUT-834CQ Mouse Anti-FGFR3 Recombinant Antibody (clone CBL546) Neut Mouse IgG1
NEUT-835CQ Mouse Anti-FGFR3 Recombinant Antibody (clone CBL547) WB, Neut Mouse IgG1
NEUT-836CQ Mouse Anti-FGFR3 Recombinant Antibody (clone 6G11) WB, Neut Mouse IgG1
NEUT-837CQ Mouse Anti-FGFR3 Recombinant Antibody (clone CBL061) WB, IHC, Neut Mouse IgG1
NEUT-838CQ Rat Anti-Fgfr3 Recombinant Antibody (clone CBL548) Neut Rat IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1299 Hi-Affi™ Rabbit Anti-FGFR3 Recombinant Antibody (clone DS1299AB) WB, IHC, ICC, FC Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0157-YC-F(E) Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0157-YC-F(E)) ELISA, IP, WB Human Fab
HPAB-0158-YC-F(E) Mouse Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0158-YC-F(E)) ELISA, FC Mouse Fab
HPAB-0159-YC-F(E) Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1); Fab Fragment ELISA, FuncS Human Fab
HPAB-0160-YC-F(E) Human Anti-FGFR3 Recombinant Antibody (clone PRO-001); Fab Fragment FC, FuncS Human Fab
HPAB-0161-YC-F(E) Human Anti-FGFR3 Recombinant Antibody (clone PRO-055); Fab Fragment FC, FuncS Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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