This immunotoxin was achieved by conjugating/fusing the Anti-FUT3 monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to human lung adenocarcinoma cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of lung adenocarcinoma.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1628z | Mouse Anti-FUT3 Recombinant Antibody (clone 5H6) | WB, ICC, IF, IHC | Mouse IgG1 |
MOB-0258CT | Recombinant Mouse anti-Human FUT3 Monoclonal antibody (3-36MF) | ELISA, ICC/IF, IHC-P, WB | |
FAMAB-1370CQ | Human Anti-FUT3 Recombinant Antibody (clone PR 5C5) | ELISA, IF, IHC | Human IgG1 |
VS2-QX25 | Mouse Anti-FUT3 Recombinant Antibody (clone BRIC 87) | ICC, IF, WB | Mouse IgM, κ |
VS2-QX87 | Mouse Anti-FUT3 Recombinant Antibody (clone MAL A) | Haemagglutination | Mouse IgM, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L017E | anti-FUT3 immunotoxin BR96 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L055E | anti-FUT3 immunotoxin BR96 (scFv)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L055R | anti-FUT3 immunotoxin BR96 (scFv)-RTA | Cytotoxicity assay, Functional assay |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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